Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50028079
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255631(N-[(1R,2R,5S)-2-{[(5-Chloroindol-2-yl)carbonyl]ami...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255577(N-{(1R,2S,5S)-2-{[(5-Chloroindol-2-yl)carbonyl]ami...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255205(N-[(1R,2S,5S)-2-{[(5-Chloroindol-2-yl)carbonyl]ami...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255207(N-{(1R,2S,5S)-2-{[(5-Chloroindol-2-yl)carbonyl]ami...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255159(N-{(1R,2S,5S)-2-{[(5-Chloroindol-2-yl)carbonyl]ami...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255204(N-[(1R,2S,5S)-2-{[(5-Chloroindol-2-yl)carbonyl]ami...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255576(N-[(1R,2S,5S)-2-{[(5-Chloroindol-2-yl)carbonyl]ami...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255575(N-[(1R,2S,5S)-2-{[(5-Chloroindol-2-yl)carbonyl]ami...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255206(N-[(1R,2S,5S)-2-{[(5-Chloroindol-2-yl)carbonyl]ami...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255578(N-[(1R,2S,5S)-2-{[(5-Chloroindol-2-yl)carbonyl]ami...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255158(N-[(1R,2S,5S)-5-(tert-Butylcarbamoyl)-2-{[(5-chlor...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255579(N-[(1R,2S,5S)-5-Acetyl-2-{[(5-chloroindol-2-yl)car...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255574(cis-(1S)-4-(5-chloro-1H-indole-2-carboxamido)-3-(5...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50255580(N-{(1R,2S,5S)-2-{[(5-Chloroindol-2-yl)carbonyl]ami...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50214995(cis-N-(2-(5-chloro-1H-indole-2-carboxamido)cyclohe...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataKi:  1.74nMAssay Description:Inhibition of rabbit factor 10a by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataKi:  2.85nMAssay Description:Inhibition of human factor 10a by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Rat)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataKi:  8.77nMAssay Description:Inhibition of rat factor 10a by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataKi:  41nMAssay Description:Inhibition of human factor 10a by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataKi:  2.54E+3nMAssay Description:Inhibition of human thrombin by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of human recombinant tissue plasminogen activator by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibition of human plasmin by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataKi:  6.82E+4nMAssay Description:Inhibition of human recombinant tissue plasminogen activator by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human recombinant factor 7a/soluble tissue factor by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM35743(CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human plasmin by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of human thrombin by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed