Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50010155
TargetCaspase-3(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM10320((S)-1-Methyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]s...)
Affinity DataKi:  15nMAssay Description:Evaluated for the dissociation constant for the inhibition of caspase-3More data for this Ligand-Target Pair
TargetCaspase-7(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM10320((S)-1-Methyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]s...)
Affinity DataKi:  47nMAssay Description:Evaluated for kinetic dissociation constant (kon) for the inhibition of caspase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091584(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataKi:  160nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091587(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataKi:  240nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091565(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataKi:  260nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091582(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataKi:  6.30E+3nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091571(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataKi:  8.80E+3nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091583(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataKi:  1.00E+4nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091578(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataKi:  1.30E+4nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091563(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataKi:  1.40E+4nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091581(3-(2-{2-[2-Acetylamino-3-(4-hydroxy-phenyl)-propio...)
Affinity DataIC50:  0.110nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091567(3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo-2H-...)
Affinity DataIC50:  0.370nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091575(5-(7,7-Dimethyl-2-oxo-bicyclo[2.2.1]hept-1-ylmetha...)
Affinity DataIC50:  0.400nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091566(3-(2-{2-[2-Acetylamino-3-(4-hydroxy-phenyl)-propio...)
Affinity DataIC50:  0.760nMAssay Description:Dissociation constant for inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091569(3-{[9-(2-Fluoro-benzoylamino)-6,10-dioxo-octahydro...)
Affinity DataIC50:  1nMAssay Description:Dissociation constant for inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091580(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataIC50:  1.70nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091572(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataIC50:  1.90nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091579(3-[(1-{2-[2-Acetylamino-3-(4-hydroxy-phenyl)-propi...)
Affinity DataIC50:  2nMAssay Description:Dissociation constant for inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091576(4-Benzooxazol-2-yl-3-{2-[(2-benzoylamino-3-methyl-...)
Affinity DataIC50:  2nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091586(4-(2-{2-[2-Acetylamino-3-(4-hydroxy-phenyl)-propio...)
Affinity DataIC50:  9nMAssay Description:Dissociation constant for inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091561(3-(2-{2-[2-Acetylamino-3-(4-hydroxy-phenyl)-propio...)
Affinity DataIC50:  9nMAssay Description:Dissociation constant for inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091589(3-({5-[(Naphthalene-1-carbonyl)-amino]-4-oxo-1,2,4...)
Affinity DataIC50:  10nMAssay Description:Dissociation constant for inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091577((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataIC50:  10nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091574(3-({4-Hydroxy-1-[3-methyl-2-(3-phenyl-allylamino)-...)
Affinity DataIC50:  13nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091570(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataIC50:  17nMAssay Description:Dissociation constant for inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091585(3-((S)-2-{(S)-2-[2-((S)-Acetylamino)-3-(4-hydroxy-...)
Affinity DataIC50:  18.5nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091588(3-[(6-Benzyloxycarbonylamino-5-oxo-octahydro-indol...)
Affinity DataIC50:  36nMAssay Description:Dissociation constant for inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091573(1-{3-Methyl-2-[(naphthalene-2-carbonyl)-amino]-but...)
Affinity DataIC50:  38nMAssay Description:Dissociation constant for inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091568(3-(2-{5-[(Naphthalene-1-carbonyl)-amino]-6-oxo-6H-...)
Affinity DataIC50:  46nMAssay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091564(3-[2-(2-Naphthalen-1-yl-ethoxy)-benzenesulfonylami...)
Affinity DataIC50:  62nMAssay Description:Dissociation constant for inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091562(3-((S)-2-{(S)-2-[(S)-2-Acetylamino-3-(4-hydroxy-ph...)
Affinity DataIC50:  2.00E+5nMAssay Description:Dissociation constant for inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50291985(3-{[1-(2-Benzyloxycarbonylamino-3-methyl-butyryl)-...)
Affinity DataKoff:  2.71E+5s-1Assay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091572(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataKoff:  1.60E+6s-1Assay Description:Evaluated for dissociation constant for the inhibition of caspase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091566(3-(2-{2-[2-Acetylamino-3-(4-hydroxy-phenyl)-propio...)
Affinity DataKoff:  3.80E+5s-1Assay Description:Evaluated for kinetic dissociation constant (kon) for the inhibition of caspase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50291983(5-(4-Benzyl-5-oxo-2,5-dihydro-furan-3-yloxy)-3-[(S...)
Affinity DataKoff:  2.52E+5s-1Assay Description:Evaluated for kinetic dissociation constant (kon) for the inhibition of caspase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091580(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataKoff:  4.30E+5s-1Assay Description:Evaluated for dissociation constant for the inhibition of caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50422308(CHEMBL71295)
Affinity DataKoff:  1.17E+5s-1Assay Description:Evaluated for kinetic dissociation constant (kon) for the inhibition of caspase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50422307(CHEMBL273689)
Affinity DataKoff:  4.07E+5s-1Assay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50291984(3-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-bu...)
Affinity DataKoff:  2.80E+5s-1Assay Description:Compound was evaluated for the inhibitory activity against caspase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50091570(3-[2-(2-Benzyloxycarbonylamino-3-methyl-butyrylami...)
Affinity DataKoff:  1.60E+5s-1Assay Description:Evaluated for kinetic dissociation constant (kon) for the inhibition of caspase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed