Compile Data Set for Download or QSAR
Found 79 Enz. Inhib. hit(s) with all data for entry = 50031244
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309707(4-fluorobenzaldehyde O-4-butoxyphenylcarbamoyl oxi...)
Show SMILES CCCCOc1ccc(NC(=O)O\N=C\c2ccc(F)cc2)cc1
Show InChI InChI=1S/C18H19FN2O3/c1-2-3-12-23-17-10-8-16(9-11-17)21-18(22)24-20-13-14-4-6-15(19)7-5-14/h4-11,13H,2-3,12H2,1H3,(H,21,22)/b20-13+
Affinity DataKi:  30nMAssay Description:Competitive inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309725(CHEMBL598764 | nicotinaldehyde O-4-(undecyloxy)phe...)
Show SMILES CCCCCCCCCCCOc1ccc(NC(=O)O\N=C\c2cccnc2)cc1
Show InChI InChI=1S/C24H33N3O3/c1-2-3-4-5-6-7-8-9-10-18-29-23-15-13-22(14-16-23)27-24(28)30-26-20-21-12-11-17-25-19-21/h11-17,19-20H,2-10,18H2,1H3,(H,27,28)/b26-20+
Affinity DataIC50: 0.150nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309712(4-fluorobenzaldehyde O-4-(nonyloxy)phenylcarbamoyl...)
Show SMILES CCCCCCCCCOc1ccc(NC(=O)O\N=C\c2ccc(F)cc2)cc1
Show InChI InChI=1S/C23H29FN2O3/c1-2-3-4-5-6-7-8-17-28-22-15-13-21(14-16-22)26-23(27)29-25-18-19-9-11-20(24)12-10-19/h9-16,18H,2-8,17H2,1H3,(H,26,27)/b25-18+
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309701(CHEMBL597430 | benzaldehyde O-4-(nonyloxy)phenylca...)
Show SMILES CCCCCCCCCOc1ccc(NC(=O)O\N=C\c2ccccc2)cc1
Show InChI InChI=1S/C23H30N2O3/c1-2-3-4-5-6-7-11-18-27-22-16-14-21(15-17-22)25-23(26)28-24-19-20-12-9-8-10-13-20/h8-10,12-17,19H,2-7,11,18H2,1H3,(H,25,26)/b24-19+
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309713(4-fluorobenzaldehyde O-4-(decyloxy)phenylcarbamoyl...)
Show SMILES CCCCCCCCCCOc1ccc(NC(=O)O\N=C\c2ccc(F)cc2)cc1
Show InChI InChI=1S/C24H31FN2O3/c1-2-3-4-5-6-7-8-9-18-29-23-16-14-22(15-17-23)27-24(28)30-26-19-20-10-12-21(25)13-11-20/h10-17,19H,2-9,18H2,1H3,(H,27,28)/b26-19+
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309711(4-fluorobenzaldehyde O-4-(octyloxy)phenylcarbamoyl...)
Show SMILES CCCCCCCCOc1ccc(NC(=O)O\N=C\c2ccc(F)cc2)cc1
Show InChI InChI=1S/C22H27FN2O3/c1-2-3-4-5-6-7-16-27-21-14-12-20(13-15-21)25-22(26)28-24-17-18-8-10-19(23)11-9-18/h8-15,17H,2-7,16H2,1H3,(H,25,26)/b24-17+
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309726(CHEMBL597940 | nicotinaldehyde O-4-(dodecyloxy)phe...)
Show SMILES CCCCCCCCCCCCOc1ccc(NC(=O)O\N=C\c2cccnc2)cc1
Show InChI InChI=1S/C25H35N3O3/c1-2-3-4-5-6-7-8-9-10-11-19-30-24-16-14-23(15-17-24)28-25(29)31-27-21-22-13-12-18-26-20-22/h12-18,20-21H,2-11,19H2,1H3,(H,28,29)/b27-21+
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309702(CHEMBL597431 | benzaldehyde O-4-(decyloxy)phenylca...)
Show SMILES CCCCCCCCCCOc1ccc(NC(=O)O\N=C\c2ccccc2)cc1
Show InChI InChI=1S/C24H32N2O3/c1-2-3-4-5-6-7-8-12-19-28-23-17-15-22(16-18-23)26-24(27)29-25-20-21-13-10-9-11-14-21/h9-11,13-18,20H,2-8,12,19H2,1H3,(H,26,27)/b25-20+
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309724(CHEMBL598558 | nicotinaldehyde O-4-(decyloxy)pheny...)
Show SMILES CCCCCCCCCCOc1ccc(NC(=O)O\N=C\c2cccnc2)cc1
Show InChI InChI=1S/C23H31N3O3/c1-2-3-4-5-6-7-8-9-17-28-22-14-12-21(13-15-22)26-23(27)29-25-19-20-11-10-16-24-18-20/h10-16,18-19H,2-9,17H2,1H3,(H,26,27)/b25-19+
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309714(4-fluorobenzaldehyde O-4-(undecyloxy)phenylcarbamo...)
Show SMILES CCCCCCCCCCCOc1ccc(NC(=O)O\N=C\c2ccc(F)cc2)cc1
Show InChI InChI=1S/C25H33FN2O3/c1-2-3-4-5-6-7-8-9-10-19-30-24-17-15-23(16-18-24)28-25(29)31-27-20-21-11-13-22(26)14-12-21/h11-18,20H,2-10,19H2,1H3,(H,28,29)/b27-20+
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309700(CHEMBL597229 | benzaldehyde O-4-(octyloxy)phenylca...)
Show SMILES CCCCCCCCOc1ccc(NC(=O)O\N=C\c2ccccc2)cc1
Show InChI InChI=1S/C22H28N2O3/c1-2-3-4-5-6-10-17-26-21-15-13-20(14-16-21)24-22(25)27-23-18-19-11-8-7-9-12-19/h7-9,11-16,18H,2-6,10,17H2,1H3,(H,24,25)/b23-18+
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309703(CHEMBL586217 | benzaldehyde O-4-(undecyloxy)phenyl...)
Show SMILES CCCCCCCCCCCOc1ccc(NC(=O)O\N=C\c2ccccc2)cc1
Show InChI InChI=1S/C25H34N2O3/c1-2-3-4-5-6-7-8-9-13-20-29-24-18-16-23(17-19-24)27-25(28)30-26-21-22-14-11-10-12-15-22/h10-12,14-19,21H,2-9,13,20H2,1H3,(H,27,28)/b26-21+
Affinity DataIC50: 0.450nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309723(CHEMBL598557 | nicotinaldehyde O-4-(nonyloxy)pheny...)
Show SMILES CCCCCCCCCOc1ccc(NC(=O)O\N=C\c2cccnc2)cc1
Show InChI InChI=1S/C22H29N3O3/c1-2-3-4-5-6-7-8-16-27-21-13-11-20(12-14-21)25-22(26)28-24-18-19-10-9-15-23-17-19/h9-15,17-18H,2-8,16H2,1H3,(H,25,26)/b24-18+
Affinity DataIC50: 0.650nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309722(CHEMBL598556 | nicotinaldehyde O-4-(octyloxy)pheny...)
Show SMILES CCCCCCCCOc1ccc(NC(=O)O\N=C\c2cccnc2)cc1
Show InChI InChI=1S/C21H27N3O3/c1-2-3-4-5-6-7-15-26-20-12-10-19(11-13-20)24-21(25)27-23-17-18-9-8-14-22-16-18/h8-14,16-17H,2-7,15H2,1H3,(H,24,25)/b23-17+
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309736(CHEMBL597923 | phenyl 4-(undecyloxy)phenylcarbamat...)
Show SMILES CCCCCCCCCCCOc1ccc(NC(=O)Oc2ccccc2)cc1
Show InChI InChI=1S/C24H33NO3/c1-2-3-4-5-6-7-8-9-13-20-27-22-18-16-21(17-19-22)25-24(26)28-23-14-11-10-12-15-23/h10-12,14-19H,2-9,13,20H2,1H3,(H,25,26)
Affinity DataIC50: 1nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309735(CHEMBL592771 | phenyl 4-(decyloxy)phenylcarbamate)
Show SMILES CCCCCCCCCCOc1ccc(NC(=O)Oc2ccccc2)cc1
Show InChI InChI=1S/C23H31NO3/c1-2-3-4-5-6-7-8-12-19-26-21-17-15-20(16-18-21)24-23(25)27-22-13-10-9-11-14-22/h9-11,13-18H,2-8,12,19H2,1H3,(H,24,25)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM26758(2-fluorophenyl N-[6-(2-methyl-4,5-diphenyl-1H-imid...)
Show SMILES Cc1nc(c(-c2ccccc2)n1CCCCCCNC(=O)Oc1ccccc1F)-c1ccccc1
Show InChI InChI=1S/C29H30FN3O2/c1-22-32-27(23-14-6-4-7-15-23)28(24-16-8-5-9-17-24)33(22)21-13-3-2-12-20-31-29(34)35-26-19-11-10-18-25(26)30/h4-11,14-19H,2-3,12-13,20-21H2,1H3,(H,31,34)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309737(CHEMBL592772 | phenyl 4-(dodecyloxy)phenylcarbamat...)
Show SMILES CCCCCCCCCCCCOc1ccc(NC(=O)Oc2ccccc2)cc1
Show InChI InChI=1S/C25H35NO3/c1-2-3-4-5-6-7-8-9-10-14-21-28-23-19-17-22(18-20-23)26-25(27)29-24-15-12-11-13-16-24/h11-13,15-20H,2-10,14,21H2,1H3,(H,26,27)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309708(4-fluorobenzaldehyde O-4-(pentyloxy)phenylcarbamoy...)
Show SMILES CCCCCOc1ccc(NC(=O)O\N=C\c2ccc(F)cc2)cc1
Show InChI InChI=1S/C19H21FN2O3/c1-2-3-4-13-24-18-11-9-17(10-12-18)22-19(23)25-21-14-15-5-7-16(20)8-6-15/h5-12,14H,2-4,13H2,1H3,(H,22,23)/b21-14+
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309689(CHEMBL597014 | propan-2-one O-4-(nonyloxy)phenylca...)
Show SMILES CCCCCCCCCOc1ccc(NC(=O)ON=C(C)C)cc1
Show InChI InChI=1S/C19H30N2O3/c1-4-5-6-7-8-9-10-15-23-18-13-11-17(12-14-18)20-19(22)24-21-16(2)3/h11-14H,4-10,15H2,1-3H3,(H,20,22)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309715(4-fluorobenzaldehyde O-4-(dodecyloxy)phenylcarbamo...)
Show SMILES CCCCCCCCCCCCOc1ccc(NC(=O)O\N=C\c2ccc(F)cc2)cc1
Show InChI InChI=1S/C26H35FN2O3/c1-2-3-4-5-6-7-8-9-10-11-20-31-25-18-16-24(17-19-25)29-26(30)32-28-21-22-12-14-23(27)15-13-22/h12-19,21H,2-11,20H2,1H3,(H,29,30)/b28-21+
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309707(4-fluorobenzaldehyde O-4-butoxyphenylcarbamoyl oxi...)
Show SMILES CCCCOc1ccc(NC(=O)O\N=C\c2ccc(F)cc2)cc1
Show InChI InChI=1S/C18H19FN2O3/c1-2-3-12-23-17-10-8-16(9-11-17)21-18(22)24-20-13-14-4-6-15(19)7-5-14/h4-11,13H,2-3,12H2,1H3,(H,21,22)/b20-13+
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309690(CHEMBL597215 | propan-2-one O-4-(decyloxy)phenylca...)
Show SMILES CCCCCCCCCCOc1ccc(NC(=O)ON=C(C)C)cc1
Show InChI InChI=1S/C20H32N2O3/c1-4-5-6-7-8-9-10-11-16-24-19-14-12-18(13-15-19)21-20(23)25-22-17(2)3/h12-15H,4-11,16H2,1-3H3,(H,21,23)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309710(4-fluorobenzaldehyde O-4-(heptyloxy)phenylcarbamoy...)
Show SMILES CCCCCCCOc1ccc(NC(=O)O\N=C\c2ccc(F)cc2)cc1
Show InChI InChI=1S/C21H25FN2O3/c1-2-3-4-5-6-15-26-20-13-11-19(12-14-20)24-21(25)27-23-16-17-7-9-18(22)10-8-17/h7-14,16H,2-6,15H2,1H3,(H,24,25)/b23-16+
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309721(CHEMBL605005 | nicotinaldehyde O-4-(heptyloxy)phen...)
Show SMILES CCCCCCCOc1ccc(NC(=O)O\N=C\c2cccnc2)cc1
Show InChI InChI=1S/C20H25N3O3/c1-2-3-4-5-6-14-25-19-11-9-18(10-12-19)23-20(24)26-22-16-17-8-7-13-21-15-17/h7-13,15-16H,2-6,14H2,1H3,(H,23,24)/b22-16+
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309704(CHEMBL596617 | benzaldehyde O-4-(dodecyloxy)phenyl...)
Show SMILES CCCCCCCCCCCCOc1ccc(NC(=O)O\N=C\c2ccccc2)cc1
Show InChI InChI=1S/C26H36N2O3/c1-2-3-4-5-6-7-8-9-10-14-21-30-25-19-17-24(18-20-25)28-26(29)31-27-22-23-15-12-11-13-16-23/h11-13,15-20,22H,2-10,14,21H2,1H3,(H,28,29)/b27-22+
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309765(CHEMBL597295 | propan-2-one O-4-(octyloxy)phenylca...)
Show SMILES CCCCCCCCOc1ccc(NC(=O)ON=C(C)C)cc1
Show InChI InChI=1S/C18H28N2O3/c1-4-5-6-7-8-9-14-22-17-12-10-16(11-13-17)19-18(21)23-20-15(2)3/h10-13H,4-9,14H2,1-3H3,(H,19,21)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309697(CHEMBL598244 | benzaldehyde O-4-(pentyloxy)phenylc...)
Show SMILES CCCCCOc1ccc(NC(=O)O\N=C\c2ccccc2)cc1
Show InChI InChI=1S/C19H22N2O3/c1-2-3-7-14-23-18-12-10-17(11-13-18)21-19(22)24-20-15-16-8-5-4-6-9-16/h4-6,8-13,15H,2-3,7,14H2,1H3,(H,21,22)/b20-15+
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309758(4-fluorophenyl 4-butoxybenzylcarbamate | CHEMBL607...)
Show SMILES CCCCOc1ccc(CNC(=O)Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C18H20FNO3/c1-2-3-12-22-16-8-4-14(5-9-16)13-20-18(21)23-17-10-6-15(19)7-11-17/h4-11H,2-3,12-13H2,1H3,(H,20,21)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309691(CHEMBL597216 | propan-2-one O-4-(undecyloxy)phenyl...)
Show SMILES CCCCCCCCCCCOc1ccc(NC(=O)ON=C(C)C)cc1
Show InChI InChI=1S/C21H34N2O3/c1-4-5-6-7-8-9-10-11-12-17-25-20-15-13-19(14-16-20)22-21(24)26-23-18(2)3/h13-16H,4-12,17H2,1-3H3,(H,22,24)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309692(CHEMBL599357 | propan-2-one O-4-(dodecyloxy)phenyl...)
Show SMILES CCCCCCCCCCCCOc1ccc(NC(=O)ON=C(C)C)cc1
Show InChI InChI=1S/C22H36N2O3/c1-4-5-6-7-8-9-10-11-12-13-18-26-21-16-14-20(15-17-21)23-22(25)27-24-19(2)3/h14-17H,4-13,18H2,1-3H3,(H,23,25)
Affinity DataIC50: 5nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309734(CHEMBL598572 | phenyl 4-(octyloxy)phenylcarbamate)
Show SMILES CCCCCCCCOc1ccc(NC(=O)Oc2ccccc2)cc1
Show InChI InChI=1S/C21H27NO3/c1-2-3-4-5-6-10-17-24-19-15-13-18(14-16-19)22-21(23)25-20-11-8-7-9-12-20/h7-9,11-16H,2-6,10,17H2,1H3,(H,22,23)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309719(CHEMBL597728 | nicotinaldehyde O-4-(pentyloxy)phen...)
Show SMILES CCCCCOc1ccc(NC(=O)O\N=C\c2cccnc2)cc1
Show InChI InChI=1S/C18H21N3O3/c1-2-3-4-12-23-17-9-7-16(8-10-17)21-18(22)24-20-14-15-6-5-11-19-13-15/h5-11,13-14H,2-4,12H2,1H3,(H,21,22)/b20-14+
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309757(CHEMBL596877 | pyridin-3-yl 4-butoxybenzylcarbamat...)
Show SMILES CCCCOc1ccc(CNC(=O)Oc2cccnc2)cc1
Show InChI InChI=1S/C17H20N2O3/c1-2-3-11-21-15-8-6-14(7-9-15)12-19-17(20)22-16-5-4-10-18-13-16/h4-10,13H,2-3,11-12H2,1H3,(H,19,20)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309709(4-fluorobenzaldehyde O-4-(hexyloxy)phenylcarbamoyl...)
Show SMILES CCCCCCOc1ccc(NC(=O)O\N=C\c2ccc(F)cc2)cc1
Show InChI InChI=1S/C20H23FN2O3/c1-2-3-4-5-14-25-19-12-10-18(11-13-19)23-20(24)26-22-15-16-6-8-17(21)9-7-16/h6-13,15H,2-5,14H2,1H3,(H,23,24)/b22-15+
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309744(2-fluorophenyl 1-(4-butoxyphenyl)propylcarbamate |...)
Show SMILES CCCCOc1ccc(cc1)C(CC)NC(=O)Oc1ccccc1F
Show InChI InChI=1S/C20H24FNO3/c1-3-5-14-24-16-12-10-15(11-13-16)18(4-2)22-20(23)25-19-9-7-6-8-17(19)21/h6-13,18H,3-5,14H2,1-2H3,(H,22,23)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309698(CHEMBL598245 | benzaldehyde O-4-(hexyloxy)phenylca...)
Show SMILES CCCCCCOc1ccc(NC(=O)O\N=C\c2ccccc2)cc1
Show InChI InChI=1S/C20H24N2O3/c1-2-3-4-8-15-24-19-13-11-18(12-14-19)22-20(23)25-21-16-17-9-6-5-7-10-17/h5-7,9-14,16H,2-4,8,15H2,1H3,(H,22,23)/b21-16+
Affinity DataIC50: 8nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309720(CHEMBL597729 | nicotinaldehyde O-4-(hexyloxy)pheny...)
Show SMILES CCCCCCOc1ccc(NC(=O)O\N=C\c2cccnc2)cc1
Show InChI InChI=1S/C19H23N3O3/c1-2-3-4-5-13-24-18-10-8-17(9-11-18)22-19(23)25-21-15-16-7-6-12-20-14-16/h6-12,14-15H,2-5,13H2,1H3,(H,22,23)/b21-15+
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309764(CHEMBL597294 | propan-2-one O-4-(heptyloxy)phenylc...)
Show SMILES CCCCCCCOc1ccc(NC(=O)ON=C(C)C)cc1
Show InChI InChI=1S/C17H26N2O3/c1-4-5-6-7-8-13-21-16-11-9-15(10-12-16)18-17(20)22-19-14(2)3/h9-12H,4-8,13H2,1-3H3,(H,18,20)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309696(CHEMBL598243 | benzaldehyde O-4-butoxyphenylcarbam...)
Show SMILES CCCCOc1ccc(NC(=O)O\N=C\c2ccccc2)cc1
Show InChI InChI=1S/C18H20N2O3/c1-2-3-13-22-17-11-9-16(10-12-17)20-18(21)23-19-14-15-7-5-4-6-8-15/h4-12,14H,2-3,13H2,1H3,(H,20,21)/b19-14+
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309733(CHEMBL599381 | phenyl 4-(heptyloxy)phenylcarbamate)
Show SMILES CCCCCCCOc1ccc(NC(=O)Oc2ccccc2)cc1
Show InChI InChI=1S/C20H25NO3/c1-2-3-4-5-9-16-23-18-14-12-17(13-15-18)21-20(22)24-19-10-7-6-8-11-19/h6-8,10-15H,2-5,9,16H2,1H3,(H,21,22)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309699(CHEMBL597228 | benzaldehyde O-4-(heptyloxy)phenylc...)
Show SMILES CCCCCCCOc1ccc(NC(=O)O\N=C\c2ccccc2)cc1
Show InChI InChI=1S/C21H26N2O3/c1-2-3-4-5-9-16-25-20-14-12-19(13-15-20)23-21(24)26-22-17-18-10-7-6-8-11-18/h6-8,10-15,17H,2-5,9,16H2,1H3,(H,23,24)/b22-17+
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309755(2,4-difluorophenyl 4-butoxybenzylcarbamate | CHEMB...)
Show SMILES CCCCOc1ccc(CNC(=O)Oc2ccc(F)cc2F)cc1
Show InChI InChI=1S/C18H19F2NO3/c1-2-3-10-23-15-7-4-13(5-8-15)12-21-18(22)24-17-9-6-14(19)11-16(17)20/h4-9,11H,2-3,10,12H2,1H3,(H,21,22)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309756(2-fluorophenyl 4-butoxybenzylcarbamate | CHEMBL596...)
Show SMILES CCCCOc1ccc(CNC(=O)Oc2ccccc2F)cc1
Show InChI InChI=1S/C18H20FNO3/c1-2-3-12-22-15-10-8-14(9-11-15)13-20-18(21)23-17-7-5-4-6-16(17)19/h4-11H,2-3,12-13H2,1H3,(H,20,21)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309739(2-fluorophenyl 4-(decyloxy)phenylcarbamate | CHEMB...)
Show SMILES CCCCCCCCCCOc1ccc(NC(=O)Oc2ccccc2F)cc1
Show InChI InChI=1S/C23H30FNO3/c1-2-3-4-5-6-7-8-11-18-27-20-16-14-19(15-17-20)25-23(26)28-22-13-10-9-12-21(22)24/h9-10,12-17H,2-8,11,18H2,1H3,(H,25,26)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309695(CHEMBL592635 | benzaldehyde O-4-propoxyphenylcarba...)
Show SMILES CCCOc1ccc(NC(=O)O\N=C\c2ccccc2)cc1
Show InChI InChI=1S/C17H18N2O3/c1-2-12-21-16-10-8-15(9-11-16)19-17(20)22-18-13-14-6-4-3-5-7-14/h3-11,13H,2,12H2,1H3,(H,19,20)/b18-13+
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309750(4-fluorophenyl 1-(4-butoxyphenyl)propylcarbamate |...)
Show SMILES CCCCOc1ccc(cc1)C(CC)NC(=O)Oc1ccc(F)cc1
Show InChI InChI=1S/C20H24FNO3/c1-3-5-14-24-17-10-6-15(7-11-17)19(4-2)22-20(23)25-18-12-8-16(21)9-13-18/h6-13,19H,3-5,14H2,1-2H3,(H,22,23)
Affinity DataIC50: 12nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309751(4-methoxyphenyl 1-(4-butoxyphenyl)propylcarbamate ...)
Show SMILES CCCCOc1ccc(cc1)C(CC)NC(=O)Oc1ccc(OC)cc1
Show InChI InChI=1S/C21H27NO4/c1-4-6-15-25-18-9-7-16(8-10-18)20(5-2)22-21(23)26-19-13-11-17(24-3)12-14-19/h7-14,20H,4-6,15H2,1-3H3,(H,22,23)
Affinity DataIC50: 12nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309752(CHEMBL597064 | phenyl 1-(4-butoxyphenyl)propylcarb...)
Show SMILES CCCCOc1ccc(cc1)C(CC)NC(=O)Oc1ccccc1
Show InChI InChI=1S/C20H25NO3/c1-3-5-15-23-17-13-11-16(12-14-17)19(4-2)21-20(22)24-18-9-7-6-8-10-18/h6-14,19H,3-5,15H2,1-2H3,(H,21,22)
Affinity DataIC50: 12nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50309754(3-chlorophenyl 4-butoxybenzylcarbamate | CHEMBL596...)
Show SMILES CCCCOc1ccc(CNC(=O)Oc2cccc(Cl)c2)cc1
Show InChI InChI=1S/C18H20ClNO3/c1-2-3-11-22-16-9-7-14(8-10-16)13-20-18(21)23-17-6-4-5-15(19)12-17/h4-10,12H,2-3,11,13H2,1H3,(H,20,21)
Affinity DataIC50: 12nMAssay Description:Inhibition of human FAAH expressed in human H4 cellsMore data for this Ligand-Target Pair
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