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Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50048519
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of rolipram binding to Phosphodiesterase 4More data for this Ligand-Target Pair
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of rolipram binding to Phosphodiesterase 4More data for this Ligand-Target Pair
LigandPNGBDBM50219407(CHEMBL84350)
Affinity DataKi:  5nMAssay Description:Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)
Affinity DataKi:  38nMAssay Description:Inhibition of rolipram binding to Phosphodiesterase 4More data for this Ligand-Target Pair
LigandPNGBDBM50219414(CHEMBL79661)
Affinity DataKi:  60nMAssay Description:Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219411(CHEMBL82934)
Affinity DataKi:  63nMAssay Description:Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219417(CHEMBL421343)
Affinity DataKi:  128nMAssay Description:Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219409(CHEMBL354743)
Affinity DataKi:  138nMAssay Description:Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50218260(CHEMBL70391)
Affinity DataKi:  149nMAssay Description:Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219404(CHEMBL79739)
Affinity DataKi:  199nMAssay Description:Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219406(CHEMBL309420)
Affinity DataKi:  208nMAssay Description:Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219413(CHEMBL81226)
Affinity DataKi:  212nMAssay Description:Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219405(CHEMBL81020)
Affinity DataKi:  235nMAssay Description:Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219410(CHEMBL311025)
Affinity DataKi:  237nMAssay Description:Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219408(CHEMBL84115)
Affinity DataKi:  397nMAssay Description:Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219416(CHEMBL167389)
Affinity DataKi:  473nMAssay Description:Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219412(CHEMBL82882)
Affinity DataKi:  498nMAssay Description:Affinity for rolipram binding site (RBS) of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human Phosphodiesterase 4More data for this Ligand-Target Pair
LigandPNGBDBM50219407(CHEMBL84350)
Affinity DataIC50:  2nMAssay Description:Inhibition of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219418(CHEMBL450274)
Affinity DataIC50:  12nMAssay Description:Inhibition of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219414(CHEMBL79661)
Affinity DataIC50:  21nMAssay Description:Inhibition of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219412(CHEMBL82882)
Affinity DataIC50:  25nMAssay Description:Inhibition of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219410(CHEMBL311025)
Affinity DataIC50:  28nMAssay Description:Inhibition of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219417(CHEMBL421343)
Affinity DataIC50:  30nMAssay Description:Inhibition of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219415(CHEMBL83872)
Affinity DataIC50:  30nMAssay Description:Inhibition of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219411(CHEMBL82934)
Affinity DataIC50:  36nMAssay Description:Inhibition of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219408(CHEMBL84115)
Affinity DataIC50:  51nMAssay Description:Inhibition of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50218260(CHEMBL70391)
Affinity DataIC50:  53nMAssay Description:Inhibition of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219404(CHEMBL79739)
Affinity DataIC50:  72nMAssay Description:Inhibition of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human Phosphodiesterase 4More data for this Ligand-Target Pair
LigandPNGBDBM50219406(CHEMBL309420)
Affinity DataIC50:  85nMAssay Description:Inhibition of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219413(CHEMBL81226)
Affinity DataIC50:  113nMAssay Description:Inhibition of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219405(CHEMBL81020)
Affinity DataIC50:  131nMAssay Description:Inhibition of human neutrophil phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  1.68E+3nMAssay Description:Inhibition of human Phosphodiesterase 4More data for this Ligand-Target Pair