Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50032785
LigandPNGBDBM50334652(3-((4-(1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)p...)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334653(5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334670(2,9-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334665(9-Chloro-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imida...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM14754(CHEMBL19224 | 1-[(3,4-dimethoxyphenyl)methyl]-6,7-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50334667(8-Methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imid...)
Affinity DataIC50: 31nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334666(7-Methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imid...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334654(2-Methyl-5-((1-methyl-4-phenyl-1H-imidazol-2-ylthi...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334662(2-Methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334664(8-Chloro-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imida...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334663(7-Chloro-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imida...)
Affinity DataIC50: 52nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334655(7-Chloro-2-methyl-5-((1-methyl-4-phenyl-1H-imidazo...)
Affinity DataIC50: 73nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334661(2,9-Dimethyl-5-((1-methyl-4-phenyl-1H-imidazol-2-y...)
Affinity DataIC50: 76nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334669(2,7-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 78nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334658(7-Methoxy-2-methyl-5-((1-methyl-4-phenyl-1H-imidaz...)
Affinity DataIC50: 83nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334659(8-Methoxy-2-methyl-5-((1-methyl-4-phenyl-1H-imidaz...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334657(9-Chloro-2-methyl-5-((1-methyl-4-phenyl-1H-imidazo...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334656(8-Chloro-2-methyl-5-((1-methyl-4-phenyl-1H-imidazo...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334660(2,7-Dimethyl-5-((1-methyl-4-phenyl-1H-imidazol-2-y...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334668(9-Methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imid...)
Affinity DataIC50: 430nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50334670(2,9-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE4D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50334653(5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE4D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50334670(2,9-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50334653(5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50334653(5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE5AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50334670(2,9-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50334653(5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334670(2,9-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50334653(5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50334670(2,9-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE5AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed