Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 50033280
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342721(CHEMBL1771259 | N1-(3-(2,6-dichloro-4-methoxypheny...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342728(CHEMBL1771260 | N1-(3-(2,6-dichloro-4-ethoxyphenyl...)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342721(CHEMBL1771259 | N1-(3-(2,6-dichloro-4-methoxypheny...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [125]sauvagin from rat recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342724(CHEMBL1771264 | N1-(3-(2,6-dichloro-4-methoxypheny...)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342726(CHEMBL1771262 | N1-(3-(2,6-dichloro-4-methoxypheny...)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342729(CHEMBL1771258 | N1-(3-(2,6-dichlorophenyl)-2,5-dim...)
Affinity DataKi:  7nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342727(CHEMBL1771261 | N1-(3-(2,6-dichloro-4-propoxypheny...)
Affinity DataKi:  8nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342731(CHEMBL1771256 | N1-cyclopentyl-N2-(3-mesityl-2,5-d...)
Affinity DataKi:  21nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342723(CHEMBL1771265 | N1-(3-(2,6-dichloro-4-methoxypheny...)
Affinity DataKi:  22nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342732(CHEMBL1771255 | N1-(3-mesityl-2,5-dimethylpyrazolo...)
Affinity DataKi:  29nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342730(CHEMBL1771257 | N1-cyclopentyl-N2-(3-(2,6-dichloro...)
Affinity DataKi:  38nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342725(CHEMBL1771263 | N1-(3-(2,6-dichloro-4-methoxypheny...)
Affinity DataKi:  141nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342722(CHEMBL1771266 | N1-(3-(2,6-dichloro-4-methoxypheny...)
Affinity DataKi:  383nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342733(CHEMBL1771254 | N1-(3-mesityl-2,5-dimethylpyrazolo...)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342734(CHEMBL1771267 | N-(2-Aminoethyl)-N-ethyl-9-mesityl...)
Affinity DataKi:  4.47E+3nMAssay Description:Binding affinity to CRHRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342733(CHEMBL1771254 | N1-(3-mesityl-2,5-dimethylpyrazolo...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to CRHRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342721(CHEMBL1771259 | N1-(3-(2,6-dichloro-4-methoxypheny...)
Affinity DataIC50:  7nMAssay Description:Antagonist activity at NPY Y1 receptor in human SK-N-MC cells assessed as inhibition of NPY-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342728(CHEMBL1771260 | N1-(3-(2,6-dichloro-4-ethoxyphenyl...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at NPY Y1 receptor in human SK-N-MC cells assessed as inhibition of NPY-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342727(CHEMBL1771261 | N1-(3-(2,6-dichloro-4-propoxypheny...)
Affinity DataIC50:  207nMAssay Description:Antagonist activity at NPY Y1 receptor in human SK-N-MC cells assessed as inhibition of NPY-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342721(CHEMBL1771259 | N1-(3-(2,6-dichloro-4-methoxypheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human NPY Y2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342721(CHEMBL1771259 | N1-(3-(2,6-dichloro-4-methoxypheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed