Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50034371
TargetProstaglandin E synthase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50361331(CHEMBL1933276)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50361332(CHEMBL1933420)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50273710(2-(4-(Biphenyl-4-ylmethylamino)-6-chloropyrimidin-...)
Affinity DataIC50: 650nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50060279(3-(4-Dodecanoyl-1,3,5-trimethyl-1H-pyrrol-2-yl)-pr...)
Affinity DataIC50: 670nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50060279(3-(4-Dodecanoyl-1,3,5-trimethyl-1H-pyrrol-2-yl)-pr...)
Affinity DataIC50: 800nMAssay Description:Inhibition of mPGES-1 in human A549 cell microsomes assessed as conversion of PGH2 into PGE2 at 0 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50060279(3-(4-Dodecanoyl-1,3,5-trimethyl-1H-pyrrol-2-yl)-pr...)
Affinity DataIC50: 800nMAssay Description:Inhibition of mPGES-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50006805(CHEMBL29097 | 3-(3-(tert-butylthio)-1-(4-chloroben...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50006805(CHEMBL29097 | 3-(3-(tert-butylthio)-1-(4-chloroben...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mPGES-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mPGES-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mPGES-1 in human A549 cell microsomes assessed as conversion of PGH2 into PGE2 at 0 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed