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Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50000093
TargetCoagulation factor IX(Rattus norvegicus)
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240469(CHEMBL4096341)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of rat coagulation factor 9aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240469(CHEMBL4096341)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240487(CHEMBL4066380 | US9969724, Example 32)
Affinity DataIC50:  13nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240470(CHEMBL4092982 | US9969724, Example 27)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240471(CHEMBL4069082 | US9969724, Example 45)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240473(CHEMBL4095415)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240472(CHEMBL4090664)
Affinity DataIC50:  18nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240489(CHEMBL4101793 | US9969724, Example 20)
Affinity DataIC50:  26nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240474(CHEMBL4082857)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240475(CHEMBL4080361 | US9969724, Example 9)
Affinity DataIC50:  32nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240476(CHEMBL4087720 | US9969724, Example 29)
Affinity DataIC50:  32nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240491(CHEMBL4065316 | US9969724, Example 11)
Affinity DataIC50:  33nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240477(CHEMBL4074983 | US9969724, Example 44)
Affinity DataIC50:  36nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240478(CHEMBL4083789)
Affinity DataIC50:  41nMAssay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240493(CHEMBL4085239 | US9969724, Example 28)
Affinity DataIC50:  45nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240479(CHEMBL4072364 | US9969724, Example 14)
Affinity DataIC50:  47nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240482(CHEMBL4069648)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240483(CHEMBL4099310 | US9969724, Example 12)
Affinity DataIC50:  62nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240488(CHEMBL4060976 | US9969724, Example 5)
Affinity DataIC50:  89nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240484(CHEMBL4085322 | US9969724, Example 1)
Affinity DataIC50:  98nMAssay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240486(CHEMBL4098387 | US9969724, Example 13)
Affinity DataIC50:  172nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240492(CHEMBL4071351)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240490(CHEMBL4103170)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240469(CHEMBL4096341)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERG by Whole-cell voltage clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240469(CHEMBL4096341)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 in liver microsomes (unknown origin) assessed as formation of acetaminophen from phenacetin in presence of NADPH by LC-MS/MS ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240469(CHEMBL4096341)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 in liver microsomes (unknown origin) assessed as formation of 4-hydroxydiclofenac from diclofenac in presence of NADPH by LC-MS/...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240469(CHEMBL4096341)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 in liver microsomes (unknown origin) assessed as formation of 4-hydroxymephenytoin from S-mephenytoin in presence of NADPH by L...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240469(CHEMBL4096341)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 in liver microsomes (unknown origin) assessed as formation of 1-hydroxybufuralol from bufuralol in presence of NADPH by LC-MS/MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240469(CHEMBL4096341)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 in liver microsomes (unknown origin) assessed as formation of 1-hydroxymidazolam from midazolam in presence of NADPH by LC-MS/MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240473(CHEMBL4095415)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240483(CHEMBL4099310 | US9969724, Example 12)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibitory activity against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240487(CHEMBL4066380 | US9969724, Example 32)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240477(CHEMBL4074983 | US9969724, Example 44)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240479(CHEMBL4072364 | US9969724, Example 14)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240475(CHEMBL4080361 | US9969724, Example 9)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240469(CHEMBL4096341)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240474(CHEMBL4082857)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240491(CHEMBL4065316 | US9969724, Example 11)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240490(CHEMBL4103170)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240489(CHEMBL4101793 | US9969724, Example 20)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240488(CHEMBL4060976 | US9969724, Example 5)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240486(CHEMBL4098387 | US9969724, Example 13)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240472(CHEMBL4090664)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240484(CHEMBL4085322 | US9969724, Example 1)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240482(CHEMBL4069648)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240478(CHEMBL4083789)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240493(CHEMBL4085239 | US9969724, Example 28)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240471(CHEMBL4069082 | US9969724, Example 45)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240470(CHEMBL4092982 | US9969724, Example 27)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Mochida Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50240476(CHEMBL4087720 | US9969724, Example 29)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human coagulation factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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