Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50012162
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554790(CHEMBL4781849)
Affinity DataEC50:  67nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in anti-IgM stimulated AKT T308 phosphorylation incubated for 1 hr by Western blot ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)
Affinity DataIC50: 6nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554790(CHEMBL4781849)
Affinity DataIC50: 14nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554803(CHEMBL4746208)
Affinity DataIC50: 17nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554798(CHEMBL4800386)
Affinity DataIC50: 18nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554816(CHEMBL4756224)
Affinity DataIC50: 19nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554796(CHEMBL4788763)
Affinity DataIC50: 26nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554806(CHEMBL4790707)
Affinity DataIC50: 29nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554807(CHEMBL4796454)
Affinity DataIC50: 32nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554797(CHEMBL4755404)
Affinity DataIC50: 33nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554814(CHEMBL4740560)
Affinity DataIC50: 34nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554799(CHEMBL4793082)
Affinity DataIC50: 40nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554801(CHEMBL4760455)
Affinity DataIC50: 45nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM184556(US9150579, B1)
Affinity DataIC50: 48nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554800(CHEMBL4776308)
Affinity DataIC50: 51nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554794(CHEMBL4797255)
Affinity DataIC50: 53nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554802(CHEMBL4782030)
Affinity DataIC50: 53nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554791(CHEMBL4745977)
Affinity DataIC50: 61nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554808(CHEMBL4787521)
Affinity DataIC50: 85nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554811(CHEMBL4753627)
Affinity DataIC50: 156nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554810(CHEMBL4758236)
Affinity DataIC50: 532nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554795(CHEMBL4760103)
Affinity DataIC50: 608nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554815(CHEMBL4796458)
Affinity DataIC50: 868nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554812(CHEMBL4785709)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554809(CHEMBL4759176)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554805(CHEMBL4760467)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554813(CHEMBL4798208)
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554793(CHEMBL4757731)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554792(CHEMBL4782662)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554804(CHEMBL4757709)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PI3Kdelta using substrate PIP2:PS and ATP incubated for 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554790(CHEMBL4781849)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin) incubated for 20 to 30 mins by P450-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554790(CHEMBL4781849)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin) incubated for 20 to 30 mins by P450-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554790(CHEMBL4781849)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin) incubated for 20 to 30 mins by P450-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554790(CHEMBL4781849)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin) incubated for 20 to 30 mins by P450-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554790(CHEMBL4781849)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) incubated for 20 to 30 mins by P450-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hefei Institutes of Physical Science

Curated by ChEMBL
LigandPNGBDBM50554790(CHEMBL4781849)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed