Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 18
TargetActin [R335K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65515(LAT-A | 76343-93-6 | LatA | Latrunculin A)
Affinity DataIC50: 40nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetActin(Baker's yeast)
Novartis Pharma

LigandPNGBDBM65515(LAT-A | 76343-93-6 | LatA | Latrunculin A)
Affinity DataIC50: 70nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetActin [R183K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65515(LAT-A | 76343-93-6 | LatA | Latrunculin A)
Affinity DataIC50: 110nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetActin(Baker's yeast)
Novartis Pharma

LigandPNGBDBM65506(SCHEMBL1889389 | CHEBI:80062 | Chivosazole F)
Affinity DataIC50: 140nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetActin [R335K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65506(SCHEMBL1889389 | CHEBI:80062 | Chivosazole F)
Affinity DataIC50: 270nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetActin [R183K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65506(SCHEMBL1889389 | CHEBI:80062 | Chivosazole F)
Affinity DataIC50: 380nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetActin [R183K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65516(CHEBI:84382 | CHEMBL2426321 | Chondramide C)
Affinity DataIC50: 1.19E+4nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetActin [R335K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65516(CHEBI:84382 | CHEMBL2426321 | Chondramide C)
Affinity DataIC50: 1.51E+4nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetActin(Baker's yeast)
Novartis Pharma

LigandPNGBDBM65516(CHEBI:84382 | CHEMBL2426321 | Chondramide C)
Affinity DataIC50: 1.67E+4nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed