Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 2138
LigandPNGBDBM17285((2R,15'S)-5,5,15'-trimethyl-6-oxospiro[oxane-2,14'...)
Affinity DataIC50: 3.20nMpH: 6.0 T: 2°CAssay Description:SPA beads conjugated to anti-mouse IgG were incubated overnight in buffer with anti-testosterone monoclonal antibody. The enzymatic reaction was moni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM17286((2R,15'S)-5'-(2-methoxyethoxy)-5,5,15'-trimethyl-6...)
Affinity DataIC50: 9.5nMpH: 6.0 T: 2°CAssay Description:SPA beads conjugated to anti-mouse IgG were incubated overnight in buffer with anti-testosterone monoclonal antibody. The enzymatic reaction was moni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM17287((2R,15'S)-5'-(2-methoxyethoxy)-5,5,15'-trimethyl-6...)
Affinity DataIC50: 13nMpH: 6.0 T: 2°CAssay Description:SPA beads conjugated to anti-mouse IgG were incubated overnight in buffer with anti-testosterone monoclonal antibody. The enzymatic reaction was moni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM17285((2R,15'S)-5,5,15'-trimethyl-6-oxospiro[oxane-2,14'...)
Affinity DataKi:  6.90nM ΔG°:  -48.5kJ/molepH: 7.5 T: 2°CAssay Description:A radioactive assay was used for the enzyme kinetics in the presence of EM1404 at different concentrations for its Ki determination. Reactions were i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)