Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 2977
LigandChemical structure of BindingDB Monomer ID 26526BDBM26526(BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...)
Affinity DataKi:  0.0600nM ΔG°:  -57.8kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26524BDBM26524((1R,2S)-1-({3-fluoro-4-[(2-phenylquinolin-4-yl)met...)
Affinity DataKi:  0.140nM ΔG°:  -55.7kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26525BDBM26525((1S,2R)-1-N-hydroxy-2-({4-[(2-phenylquinolin-4-yl)...)
Affinity DataKi:  0.180nM ΔG°:  -55.1kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 23487BDBM23487((1S,2R)-1-N-hydroxy-2-({4-[(2-methylquinolin-4-yl)...)
Affinity DataKi:  3nM ΔG°:  -48.2kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26527BDBM26527((1S,3R)-6-{3-fluoro-4-[(2-phenylquinolin-4-yl)meth...)
Affinity DataKi:  6.70nM ΔG°:  -46.2kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26528BDBM26528((1S,3R)-N-hydroxy-4-oxo-6-{4-[(2-phenylquinolin-4-...)
Affinity DataKi:  30nM ΔG°:  -42.5kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26529BDBM26529((1S,3R)-N-hydroxy-4-oxo-6-(4-{[2-(pyridin-3-yl)qui...)
Affinity DataKi:  32nM ΔG°:  -42.3kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26530BDBM26530((1S,3R)-N-hydroxy-6-{4-[(2-methylquinolin-4-yl)met...)
Affinity DataKi:  32nM ΔG°:  -42.3kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26531BDBM26531((1S,3R)-N-hydroxy-4-oxo-6-(4-{[2-(pyridin-4-yl)qui...)
Affinity DataKi:  33nM ΔG°:  -42.3kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26534BDBM26534((1S,3R)-6-{3-fluoro-4-[(2-phenylquinolin-4-yl)meth...)
Affinity DataKi:  40nM ΔG°:  -41.8kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26532BDBM26532((1S,3R)-N-hydroxy-4-oxo-6-(4-{[2-(trifluoromethyl)...)
Affinity DataKi:  53nM ΔG°:  -41.1kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26535BDBM26535((1S,3R)-6-{3-fluoro-4-[(2-phenylquinolin-4-yl)meth...)
Affinity DataKi:  94nM ΔG°:  -39.7kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26533BDBM26533((1S,3R)-6-{3-fluoro-4-[(2-phenylquinolin-4-yl)meth...)
Affinity DataKi:  137nM ΔG°:  -38.8kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26536BDBM26536((1S,3R)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy...)
Affinity DataKi:  143nM ΔG°:  -38.7kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26537BDBM26537((1S,3R)-4-oxo-6-(4-{[2-(pyridin-4-yl)quinolin-4-yl...)
Affinity DataKi:  673nM ΔG°:  -34.9kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26538BDBM26538((1S,3R)-4-oxo-6-(4-{[2-(trifluoromethyl)quinolin-4...)
Affinity DataKi:  2.14E+3nM ΔG°:  -32.0kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26539BDBM26539((1S,3R)-6-{4-[(2-methylquinolin-4-yl)methoxy]pheny...)
Affinity DataKi:  3.07E+3nM ΔG°:  -31.1kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26540BDBM26540((1S,3R)-4-oxo-6-(4-{[2-(pyridin-3-yl)quinolin-4-yl...)
Affinity DataKi:  3.22E+3nM ΔG°:  -31.0kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 26541BDBM26541(methyl (1S,3R)-6-{3-fluoro-4-[(2-phenylquinolin-4-...)
Affinity DataKi: >5.00E+4nM ΔG°: >-24.3kJ/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2009
Entry Details Article
PubMed