Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 3077
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27707(CHEMBL481511 | 4-{1-[3-(8-chloro-4-oxo-3,4-dihydro...)
Affinity DataIC50: 3nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27720(3-(4-chlorophenyl)quinoxaline-5-carboxamide | quin...)
Affinity DataIC50: 7nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27723(CHEMBL519443 | 3-(4-methoxyphenyl)quinoxaline-5-ca...)
Affinity DataIC50: 8nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27721(CHEMBL481603 | 3-(4-cyanophenyl)quinoxaline-5-carb...)
Affinity DataIC50: 8nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27724(3-(4-aminophenyl)quinoxaline-5-carboxamide | CHEMB...)
Affinity DataIC50: 9nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27711(2-{3-[4-(4-chlorophenyl)piperazin-1-yl]propyl}-3,4...)
Affinity DataIC50: 11nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27722(CHEMBL521428 | 3-[4-(trifluoromethyl)phenyl]quinox...)
Affinity DataIC50: 11nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)
Affinity DataIC50: 13nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27719(3-phenylquinoxaline-5-carboxamide | quinoxaline an...)
Affinity DataIC50: 14nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27709(CHEMBL401843 | 2-{3-[4-(4-fluorophenyl)-1,2,3,6-te...)
Affinity DataIC50: 16nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27705(2-[3-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)prop...)
Affinity DataIC50: 21nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27706(CHEMBL251029 | 8-chloro-2-[3-(4-phenyl-1,2,3,6-tet...)
Affinity DataIC50: 23nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27720(3-(4-chlorophenyl)quinoxaline-5-carboxamide | quin...)
Affinity DataIC50: 33nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27717(4-{4-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin...)
Affinity DataIC50: 49nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27714(CHEMBL361054 | 5-fluoro-1-[4-(4-phenyl-1,2,3,6-tet...)
Affinity DataIC50: 60nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27710(5-Chloro-2-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-y...)
Affinity DataIC50: 68nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27713(1-[4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)buty...)
Affinity DataIC50: 70nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27723(CHEMBL519443 | 3-(4-methoxyphenyl)quinoxaline-5-ca...)
Affinity DataIC50: 71nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27718(CHEMBL194482 | 2-[3-(4-Phenyl-3,6-dihydro-2H-pyrid...)
Affinity DataIC50: 82nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27714(CHEMBL361054 | 5-fluoro-1-[4-(4-phenyl-1,2,3,6-tet...)
Affinity DataIC50: 83nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27718(CHEMBL194482 | 2-[3-(4-Phenyl-3,6-dihydro-2H-pyrid...)
Affinity DataIC50: 84nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27717(4-{4-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin...)
Affinity DataIC50: 84nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27724(3-(4-aminophenyl)quinoxaline-5-carboxamide | CHEMB...)
Affinity DataIC50: 87nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27707(CHEMBL481511 | 4-{1-[3-(8-chloro-4-oxo-3,4-dihydro...)
Affinity DataIC50: 87nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27716(4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]...)
Affinity DataIC50: 90nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27721(CHEMBL481603 | 3-(4-cyanophenyl)quinoxaline-5-carb...)
Affinity DataIC50: 101nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27722(CHEMBL521428 | 3-[4-(trifluoromethyl)phenyl]quinox...)
Affinity DataIC50: 118nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27716(4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]...)
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27713(1-[4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)buty...)
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27719(3-phenylquinoxaline-5-carboxamide | quinoxaline an...)
Affinity DataIC50: 131nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27709(CHEMBL401843 | 2-{3-[4-(4-fluorophenyl)-1,2,3,6-te...)
Affinity DataIC50: 167nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27711(2-{3-[4-(4-chlorophenyl)piperazin-1-yl]propyl}-3,4...)
Affinity DataIC50: 300nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)
Affinity DataIC50: 500nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27705(2-[3-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)prop...)
Affinity DataIC50: 608nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27706(CHEMBL251029 | 8-chloro-2-[3-(4-phenyl-1,2,3,6-tet...)
Affinity DataIC50: 610nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27710(5-Chloro-2-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-y...)
Affinity DataIC50: 630nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27712(5-chloro-2-methyl-3,4-dihydroquinazolin-4-one | CH...)
Affinity DataIC50: 660nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27715(5-fluoro-1-[4-(4-phenylcyclohex-3-en-1-yl)butyl]-1...)
Affinity DataIC50: 1.00E+3nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27712(5-chloro-2-methyl-3,4-dihydroquinazolin-4-one | CH...)
Affinity DataIC50: 1.20E+3nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27506(CHEMBL81977 | 3-aminobenzamide | 3-AB)
Affinity DataIC50: 9.81E+3nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27506(CHEMBL81977 | 3-aminobenzamide | 3-AB)
Affinity DataIC50: 1.12E+4nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed