Compile Data Set for Download or QSAR
Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 4808
TargetCarbonic anhydrase 7(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82103(Investigational agent, 4)
Affinity DataKi:  0.5nM ΔG°:  -52.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 7(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM50210256(CHEMBL26300 | Topiramate, 3 | Sulfamic acid (3aS,5...)
Affinity DataKi:  0.900nM ΔG°:  -50.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82103(Investigational agent, 4)
Affinity DataKi:  0.900nM ΔG°:  -50.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 7(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82104(Investigational agent, 5)
Affinity DataKi:  1.30nM ΔG°:  -49.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM50210256(CHEMBL26300 | Topiramate, 3 | Sulfamic acid (3aS,5...)
Affinity DataKi:  3.80nM ΔG°:  -47.3kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82104(Investigational agent, 5)
Affinity DataKi:  4.70nM ΔG°:  -46.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82103(Investigational agent, 4)
Affinity DataKi:  4.90nM ΔG°:  -46.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10888(Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...)
Affinity DataKi:  5.10nM ΔG°:  -46.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 7(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  6nM ΔG°:  -46.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82104(Investigational agent, 5)
Affinity DataKi:  7.80nM ΔG°:  -45.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  9nM ΔG°:  -45.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM50210256(CHEMBL26300 | Topiramate, 3 | Sulfamic acid (3aS,5...)
Affinity DataKi:  10nM ΔG°:  -44.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82103(Investigational agent, 4)
Affinity DataKi:  10nM ΔG°:  -44.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82104(Investigational agent, 5)
Affinity DataKi:  13nM ΔG°:  -44.3kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 14(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82103(Investigational agent, 4)
Affinity DataKi:  13nM ΔG°:  -44.3kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 14(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82104(Investigational agent, 5)
Affinity DataKi:  15nM ΔG°:  -43.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10888(Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...)
Affinity DataKi:  20nM ΔG°:  -43.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 4(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82104(Investigational agent, 5)
Affinity DataKi:  30nM ΔG°:  -42.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM50210256(CHEMBL26300 | Topiramate, 3 | Sulfamic acid (3aS,5...)
Affinity DataKi:  30nM ΔG°:  -42.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 6(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82104(Investigational agent, 5)
Affinity DataKi:  31nM ΔG°:  -42.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82103(Investigational agent, 4)
Affinity DataKi:  34nM ΔG°:  -41.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 13(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82103(Investigational agent, 4)
Affinity DataKi:  34nM ΔG°:  -41.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10888(Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...)
Affinity DataKi:  35nM ΔG°:  -41.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 13(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82104(Investigational agent, 5)
Affinity DataKi:  39nM ΔG°:  -41.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  43nM ΔG°:  -41.3kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82104(Investigational agent, 5)
Affinity DataKi:  45nM ΔG°:  -41.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 6(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM50210256(CHEMBL26300 | Topiramate, 3 | Sulfamic acid (3aS,5...)
Affinity DataKi:  45nM ΔG°:  -41.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 6(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82103(Investigational agent, 4)
Affinity DataKi:  46nM ΔG°:  -41.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 13(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM50210256(CHEMBL26300 | Topiramate, 3 | Sulfamic acid (3aS,5...)
Affinity DataKi:  47nM ΔG°:  -41.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10888(Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...)
Affinity DataKi:  56nM ΔG°:  -40.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  56nM ΔG°:  -40.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 4(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82103(Investigational agent, 4)
Affinity DataKi:  56nM ΔG°:  -40.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM50210256(CHEMBL26300 | Topiramate, 3 | Sulfamic acid (3aS,5...)
Affinity DataKi:  58nM ΔG°:  -40.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM50210256(CHEMBL26300 | Topiramate, 3 | Sulfamic acid (3aS,5...)
Affinity DataKi:  63nM ΔG°:  -40.4kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82103(Investigational agent, 4)
Affinity DataKi:  78nM ΔG°:  -39.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  81nM ΔG°:  -39.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 6(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10888(Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...)
Affinity DataKi:  89nM ΔG°:  -39.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  91nM ΔG°:  -39.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 4(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  95nM ΔG°:  -39.4kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 7(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10888(Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...)
Affinity DataKi:  117nM ΔG°:  -38.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 6(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  134nM ΔG°:  -38.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82104(Investigational agent, 5)
Affinity DataKi:  135nM ΔG°:  -38.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM50210256(CHEMBL26300 | Topiramate, 3 | Sulfamic acid (3aS,5...)
Affinity DataKi:  250nM ΔG°:  -37.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  374nM ΔG°:  -36.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 13(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM10888(Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...)
Affinity DataKi:  430nM ΔG°:  -35.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82104(Investigational agent, 5)
Affinity DataKi:  810nM ΔG°:  -34.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM82103(Investigational agent, 4)
Affinity DataKi:  850nM ΔG°:  -34.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 13(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  1.45E+3nM ΔG°:  -32.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 14(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM50210256(CHEMBL26300 | Topiramate, 3 | Sulfamic acid (3aS,5...)
Affinity DataKi:  1.46E+3nM ΔG°:  -32.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 14(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM26999(Ospolot | CHEMBL328560 | Contravul | Sulthiame, 2 ...)
Affinity DataKi:  1.54E+3nM ΔG°:  -32.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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