Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50001200
TargetRAC-alpha serine/threonine-protein kinase(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271974(CHEMBL4128457)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant AKT1 expressed in insect cells incubated for 60 mins measured at apparent ATP Km level by kinase ADP-FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetRAC-alpha serine/threonine-protein kinase(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271973(CHEMBL4126067)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant AKT1 expressed in insect cells incubated for 60 mins measured at apparent ATP Km level by kinase ADP-FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271976(LY 2584702 | LY-2584702 | LY2584702)
Affinity DataIC50: 4nMAssay Description:Inhibition of human p70S6K measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271964(CHEMBL4129379)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant AKT1 expressed in insect cells incubated for 60 mins measured at apparent ATP Km level by kinase ADP-FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271975(CHEMBL4129817)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant AKT1 expressed in insect cells incubated for 60 mins measured at apparent ATP Km level by kinase ADP-FP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRibosomal protein S6 kinase alpha-1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271974(CHEMBL4128457)
Affinity DataIC50: 20nMAssay Description:Inhibition of human RSK1 measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271974(CHEMBL4128457)
Affinity DataIC50: 35nMAssay Description:Inhibition of human p70S6K measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetProtein kinase C beta type(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271974(CHEMBL4128457)
Affinity DataIC50: 36nMAssay Description:Inhibition of human PKCbeta2 measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271974(CHEMBL4128457)
Affinity DataIC50: 39nMAssay Description:Inhibition of AKT1 in human U87MG cells assessed as reduction in GSK3beta Ser9 phosphorylation incubated for 1 hr by alpha screen Surefire assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetRAC-alpha serine/threonine-protein kinase(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271964(CHEMBL4129379)
Affinity DataIC50: 92nMAssay Description:Inhibition of AKT1 in human U87MG cells assessed as reduction in GSK3beta Ser9 phosphorylation incubated for 1 hr by alpha screen Surefire assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271973(CHEMBL4126067)
Affinity DataIC50: 230nMAssay Description:Inhibition of AKT1 in human U87MG cells assessed as reduction in GSK3beta Ser9 phosphorylation incubated for 1 hr by alpha screen Surefire assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRibosomal protein S6 kinase alpha-1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271975(CHEMBL4129817)
Affinity DataIC50: 272nMAssay Description:Inhibition of human RSK1 measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271964(CHEMBL4129379)
Affinity DataIC50: 399nMAssay Description:Inhibition of human p70S6K measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRibosomal protein S6 kinase alpha-1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271964(CHEMBL4129379)
Affinity DataIC50: 568nMAssay Description:Inhibition of human RSK1 measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRibosomal protein S6 kinase alpha-1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271973(CHEMBL4126067)
Affinity DataIC50: 699nMAssay Description:Inhibition of human RSK1 measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271975(CHEMBL4129817)
Affinity DataIC50: 876nMAssay Description:Inhibition of human p70S6K measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271973(CHEMBL4126067)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human p70S6K measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271975(CHEMBL4129817)
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of AKT1 in human U87MG cells assessed as reduction in GSK3beta Ser9 phosphorylation incubated for 1 hr by alpha screen Surefire assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein kinase C beta type(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271964(CHEMBL4129379)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human PKCbeta2 measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein kinase C beta type(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271975(CHEMBL4129817)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of human PKCbeta2 measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRho-associated protein kinase 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271974(CHEMBL4128457)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of histidine-tagged human recombinant ROCK2 (11 to 552 residues) expressed in insect cells using RFARKGSLRQKNV substrate incubated for 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetRho-associated protein kinase 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271975(CHEMBL4129817)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of histidine-tagged human recombinant ROCK2 (11 to 552 residues) expressed in insect cells using RFARKGSLRQKNV substrate incubated for 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRho-associated protein kinase 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271973(CHEMBL4126067)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of histidine-tagged human recombinant ROCK2 (11 to 552 residues) expressed in insect cells using RFARKGSLRQKNV substrate incubated for 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetRho-associated protein kinase 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271964(CHEMBL4129379)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of histidine-tagged human recombinant ROCK2 (11 to 552 residues) expressed in insect cells using RFARKGSLRQKNV substrate incubated for 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProtein kinase C beta type(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50271973(CHEMBL4126067)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human PKCbeta2 measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed