Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50001675
TargetCysteinyl leukotriene receptor 1/2(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50009075(CHEMBL22033 | ICI 198615 | [1-(4-Benzenesulfonylam...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity to inhibit Inophore-induced arachidonic acid metabolism (inhibition of TXB2 formation) in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM7962(CHEMBL537708 | 4-[2-(1H-imidazol-1-yl)ethoxy]benzo...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity to inhibit Inophore-induced arachidonic acid metabolism (inhibition of TXB2 formation) in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228307(CGP-35949)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228313(CHEMBL55714)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50017208(CHEMBL54744 | 6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity of compound to block binding of [3H]leukotriene D4 to Cysteinyl leukotriene D4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50000838(CHEMBL416657 | Sodium; 3-[3-tert-butylsulfanyl-1-(...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity to inhibit Inophore-induced arachidonic acid metabolism (inhibition of TXB2 formation) in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228304(CHEMBL417028)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228311(CHEMBL53333)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50009071(Ro-23-3544 | 6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-p...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity of compound to block binding of [3H]leukotriene D4 to Cysteinyl leukotriene D4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50017201(CHEMBL54955 | 6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro activity to inhibit binding of [3H]- leukotriene D4 to receptor sites in guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228301(CHEMBL54688)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228300(CHEMBL293529)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50017202(CHEMBL53252 | 6-Acetyl-7-[6-(4-acetyl-3-hydroxy-2-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of compound to block binding of [3H]leukotriene D4 to Cysteinyl leukotriene D4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50017209(CHEMBL55750 | 6-Acetyl-7-[3-(4-acetyl-3-hydroxy-2-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity of compound to block binding of [3H]leukotriene D4 to Cysteinyl leukotriene D4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50009071(Ro-23-3544 | 6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-p...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity to inhibit Inophore-induced arachidonic acid metabolism (inhibition of TXB2 formation) in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228302(CHEMBL53512)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50006806(C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50017200(CHEMBL53347 | 6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity of compound to block binding of [3H]leukotriene D4 to Cysteinyl leukotriene D4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228303(CHEMBL52877)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity to block binding of [3H]leukotriene D4 to LTD4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50017199(CHEMBL51739 | 6-Acetyl-7-[3-(4-acetyl-3-hydroxy-2-...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity of compound to block binding of [3H]leukotriene D4 to Cysteinyl leukotriene D4 receptor sites in homogenized guinea pig lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50228306(CHEMBL55164)
Affinity DataIC50: 8.00E+3nMAssay Description:In vitro activity to inhibit binding of [3H]- leukotriene D4 to receptor sites in guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50009071(Ro-23-3544 | 6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-p...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50017210(CHEMBL52351 | 8-(1,2-Dimethyl-propyl)-purine-2,6-d...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM10847(Theophylline (1,3-dimethylxanthine) | 1,3-dimethyl...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed