Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50004399
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50482547(BULGARIALACTONE B)
Affinity DataEC50:  1.68E+4nMAssay Description:Inhibition of HSP90 in human A431 cells assessed as down-regulation of Akt protein after 24 hrs by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50482547(BULGARIALACTONE B)
Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of HSP90 in human A431 cells assessed as down-regulation of survivin protein after 24 hrs by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50482548(CHEMBL1215537)
Affinity DataEC50:  8.93E+3nMAssay Description:Inhibition of HSP90 in human A431 cells assessed as down-regulation of Akt protein after 24 hrs by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50482548(CHEMBL1215537)
Affinity DataEC50:  4.93E+3nMAssay Description:Inhibition of HSP90 in human A431 cells assessed as down-regulation of Cdk4 protein after 24 hrs by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50482548(CHEMBL1215537)
Affinity DataEC50:  2.32E+3nMAssay Description:Inhibition of HSP90 in human A431 cells assessed as down-regulation of survivin protein after 24 hrs by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50482547(BULGARIALACTONE B)
Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of HSP90 in human A431 cells assessed as down-regulation of EGFR protein after 24 hrs by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50482548(CHEMBL1215537)
Affinity DataEC50:  3.57E+3nMAssay Description:Inhibition of HSP90 in human A431 cells assessed as down-regulation of EGFR protein after 24 hrs by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50482547(BULGARIALACTONE B)
Affinity DataEC50:  8.49E+3nMAssay Description:Inhibition of HSP90 in human A431 cells assessed as down-regulation of Cdk4 protein after 24 hrs by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed