Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50005685
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493642(CHEMBL2437452)
Affinity DataKd:  3.66E+4nMAssay Description:Binding affinity to human recombinant BACE1 expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493641(CHEMBL2437454)
Affinity DataKd:  2.68E+4nMAssay Description:Binding affinity to human recombinant BACE1 expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50226448((R)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
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PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493633(CHEMBL2437434)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493644(CHEMBL2437437)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493654(CHEMBL2437444)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493647(CHEMBL2437436)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493635(CHEMBL2437441)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493634(CHEMBL2437438)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493650(CHEMBL2437443)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493637(CHEMBL2437446)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493643(CHEMBL2437442)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493655(CHEMBL2437439)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493649(CHEMBL2434994)
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493641(CHEMBL2437454)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493636(CHEMBL2437440)
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493648(CHEMBL2437445)
Affinity DataIC50: 2.33E+4nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493642(CHEMBL2437452)
Affinity DataIC50: 4.14E+4nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493646(CHEMBL2437449)
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493645(CHEMBL2437456)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493640(CHEMBL2437455)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493651(CHEMBL2437450)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493652(CHEMBL2437453)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493653(CHEMBL2437447)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493639(CHEMBL2437451)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493638(CHEMBL2437448)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed