Report error Found 101 Enz. Inhib. hit(s) with all data for entry = 50005961
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0720nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.110nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.150nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.170nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.220nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.240nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.260nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.310nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.320nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.340nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.380nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
