Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50006230
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498024(CHEMBL3326332)
Affinity DataIC50: 73nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498018(CHEMBL3326331)
Affinity DataIC50: 97nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498026(CHEMBL3326319)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498028(CHEMBL3326325)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498030(CHEMBL3326326)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498019(CHEMBL3326322)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498020(CHEMBL3326320)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498021(CHEMBL3326327)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498022(CHEMBL3326328)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498023(CHEMBL3326330)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498025(CHEMBL3326324)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498027(CHEMBL3326329)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Rat)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50498029(CHEMBL3326323)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1/2 in rat IEC6 cells assessed as reduction in ERK1/2 loop phosphorylation dosed 30 mins before to stimulation with 10% serum for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed