Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50007559
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510530(CHEMBL4449293)
Affinity DataIC50: 3.60nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510513(CHEMBL4531148)
Affinity DataIC50: 4.5nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510524(CHEMBL4525220)
Affinity DataIC50: 4.90nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510530(CHEMBL4449293)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510514(CHEMBL4453695)
Affinity DataIC50: 7.40nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510529(CHEMBL4453785)
Affinity DataIC50: 8.20nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510519(CHEMBL4463377)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510519(CHEMBL4463377)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510514(CHEMBL4453695)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510516(CHEMBL4531747)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510523(CHEMBL4440833)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510525(CHEMBL4444631)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510515(CHEMBL4579375)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510513(CHEMBL4531148)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510528(CHEMBL4586004)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510516(CHEMBL4531747)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510522(CHEMBL4472623)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510532(CHEMBL4584977)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510525(CHEMBL4444631)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510531(CHEMBL4579740)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510528(CHEMBL4586004)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510517(CHEMBL4459986)
Affinity DataIC50: 47nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510518(CHEMBL4470592)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510521(CHEMBL4460273)
Affinity DataIC50: 72nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510522(CHEMBL4472623)
Affinity DataIC50: 75nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510518(CHEMBL4470592)
Affinity DataIC50: 75nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510521(CHEMBL4460273)
Affinity DataIC50: 76nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510527(CHEMBL4474419)
Affinity DataIC50: 89nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510532(CHEMBL4584977)
Affinity DataIC50: 90nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510520(CHEMBL4587723)
Affinity DataIC50: 94nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510517(CHEMBL4459986)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510523(CHEMBL4440833)
Affinity DataIC50: 104nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510531(CHEMBL4579740)
Affinity DataIC50: 108nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510529(CHEMBL4453785)
Affinity DataIC50: 109nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510524(CHEMBL4525220)
Affinity DataIC50: 118nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Rat)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510514(CHEMBL4453695)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510515(CHEMBL4579375)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510520(CHEMBL4587723)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510527(CHEMBL4474419)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510526(CHEMBL4519645)
Affinity DataIC50: 220nMAssay Description:Antagonist activity at P2X7R in LPS-stimulated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preincubated for 30 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510526(CHEMBL4519645)
Affinity DataIC50: 230nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Rat)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510530(CHEMBL4449293)
Affinity DataIC50: 549nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Rat)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510513(CHEMBL4531148)
Affinity DataIC50: 640nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Mouse)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510513(CHEMBL4531148)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at mouse P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Mouse)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510524(CHEMBL4525220)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at mouse P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Mouse)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510530(CHEMBL4449293)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at mouse P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Mouse)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510529(CHEMBL4453785)
Affinity DataIC50: 2.04E+3nMAssay Description:Antagonist activity at mouse P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Mouse)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510514(CHEMBL4453695)
Affinity DataIC50: 3.69E+3nMAssay Description:Antagonist activity at mouse P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Rat)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510525(CHEMBL4444631)
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetP2X purinoceptor 7(Mouse)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM50510525(CHEMBL4444631)
Affinity DataIC50: 4.83E+3nMAssay Description:Antagonist activity at mouse P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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