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Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50009219
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526264(CHEMBL4452694)
Affinity DataKi:  2.80nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526265(CHEMBL4520656)
Affinity DataKi:  4.5nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526262(CHEMBL4439989)
Affinity DataKi:  5.10nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526260(CHEMBL4554639)
Affinity DataKi:  5.90nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526261(CHEMBL4565664)
Affinity DataKi:  5.90nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526258(CHEMBL4455995)
Affinity DataKi:  10nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526259(CHEMBL4565745)
Affinity DataKi:  10nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526257(CHEMBL4555282)
Affinity DataKi:  12nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526263(CHEMBL4475547)
Affinity DataKi:  14nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526256(CHEMBL4551183)
Affinity DataKi:  17nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)
Affinity DataKi:  55nMAssay Description:Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526262(CHEMBL4439989)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of mouse GAT-1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526257(CHEMBL4555282)
Affinity DataIC50:  28nMAssay Description:Inhibition of mouse GAT-1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526264(CHEMBL4452694)
Affinity DataIC50:  32nMAssay Description:Inhibition of mouse GAT-1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526258(CHEMBL4455995)
Affinity DataIC50:  39nMAssay Description:Inhibition of mouse GAT-1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50426075(CHEMBL473104)
Affinity DataIC50:  40nMAssay Description:Inhibition of GAT-1 in rat brain homogenate assessed as decrease in [3H]GABA uptake preincubated for 8 mins followed by [3H]GABA addition and measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526265(CHEMBL4520656)
Affinity DataIC50:  56nMAssay Description:Inhibition of mouse GAT-1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526261(CHEMBL4565664)
Affinity DataIC50:  60nMAssay Description:Inhibition of mouse GAT-1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526259(CHEMBL4565745)
Affinity DataIC50:  66nMAssay Description:Inhibition of mouse GAT-1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)
Affinity DataIC50:  70nMAssay Description:Inhibition of GAT-1 in rat brain homogenate assessed as decrease in [3H]GABA uptake preincubated for 8 mins followed by [3H]GABA addition and measure...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50426074(CHEMBL2315957)
Affinity DataIC50:  80nMAssay Description:Inhibition of GAT-1 in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526263(CHEMBL4475547)
Affinity DataIC50:  85nMAssay Description:Inhibition of mouse GAT-1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526260(CHEMBL4554639)
Affinity DataIC50:  102nMAssay Description:Inhibition of mouse GAT-1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50003634(1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carboxyli...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human GAT1 expressed in COS cells assessed as decrease in [3H]GABA uptake after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526256(CHEMBL4551183)
Affinity DataIC50:  170nMAssay Description:Inhibition of mouse GAT-1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human GAT1 expressed in COS cells assessed as decrease in [3H]GABA uptake after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50020883((R)-Piperidine-3-carboxylic acid | (R)-nipecotic a...)
Affinity DataIC50:  5.96E+3nMAssay Description:Inhibition of human GAT1 expressed in COS cells assessed as decrease in [3H]GABA uptake after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50003624((RS)-nipecotic acid | CHEMBL277498 | Nipecotic | P...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human GAT1 expressed in COS cells assessed as decrease in [3H]GABA uptake after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM90787(1,2,3,6-tetrahydropyridine-5-carboxylic acid;hydro...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human GAT1 expressed in COS cells assessed as decrease in [3H]GABA uptake after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526256(CHEMBL4551183)
Affinity DataIC50:  1.78E+4nMAssay Description:Inhibition of mouse GAT-2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526256(CHEMBL4551183)
Affinity DataIC50:  3.24E+4nMAssay Description:Inhibition of mouse GAT-4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526256(CHEMBL4551183)
Affinity DataIC50:  3.31E+4nMAssay Description:Inhibition of mouse GAT-3 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526257(CHEMBL4555282)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of mouse GAT-2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526261(CHEMBL4565664)
Affinity DataIC50:  4.27E+4nMAssay Description:Inhibition of mouse GAT-2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526258(CHEMBL4455995)
Affinity DataIC50:  4.57E+4nMAssay Description:Inhibition of mouse GAT-2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526261(CHEMBL4565664)
Affinity DataIC50:  5.75E+4nMAssay Description:Inhibition of mouse GAT-3 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526261(CHEMBL4565664)
Affinity DataIC50:  6.31E+4nMAssay Description:Inhibition of mouse GAT-4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526258(CHEMBL4455995)
Affinity DataIC50:  6.61E+4nMAssay Description:Inhibition of mouse GAT-3 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526258(CHEMBL4455995)
Affinity DataIC50:  7.08E+4nMAssay Description:Inhibition of mouse GAT-4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526257(CHEMBL4555282)
Affinity DataIC50:  7.24E+4nMAssay Description:Inhibition of mouse GAT-4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50526257(CHEMBL4555282)
Affinity DataIC50:  9.12E+4nMAssay Description:Inhibition of mouse GAT-3 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Ludwig-Maximilians-University M£Nchen

Curated by ChEMBL
LigandPNGBDBM50020888((S)-Piperidine-3-carboxylic acid | (S)-nipecotic a...)
Affinity DataIC50:  1.16E+5nMAssay Description:Inhibition of human GAT1 expressed in COS cells assessed as decrease in [3H]GABA uptake after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed