Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50009799
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50005781(CHEBI:65324 | ALVESPIMYCIN)
Affinity DataIC50: 24nMAssay Description:Inhibition of Hsp90 in human SKBR3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50005781(CHEBI:65324 | ALVESPIMYCIN)
Affinity DataIC50: 24nMAssay Description:Inhibition of Hsp90 in human SKBR3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50008057(CHEBI:64153 | BMS-722782 | TANESPIMYCIN)
Affinity DataIC50: 33nMAssay Description:Inhibition of Hsp90 in human SKBR3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50008057(CHEBI:64153 | BMS-722782 | TANESPIMYCIN)
Affinity DataIC50: 33nMAssay Description:Inhibition of Hsp90 in human SKBR3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50191367(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataIC50: 62nMAssay Description:Inhibition of imatinib-resistant PDGFR D842V mutant (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50191367(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataIC50: 62nMAssay Description:Inhibition of imatinib-resistant PDGFR D842V mutant (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50439621(STA-9090 | GANETESPIB)
Affinity DataIC50: 63nMAssay Description:Inhibition of Hsp90 in human MG63 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50439621(STA-9090 | GANETESPIB)
Affinity DataIC50: 63nMAssay Description:Inhibition of Hsp90 in human MG63 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50: 70nMAssay Description:Inhibition of Hsp90 in human SKBR3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50: 70nMAssay Description:Inhibition of Hsp90 in human SKBR3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50191367(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataIC50: 307nMAssay Description:Inhibition of Hsp90 in human MM1S cells by BODIPY-AG fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50191367(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataIC50: 307nMAssay Description:Inhibition of Hsp90 in human MM1S cells by BODIPY-AG fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 642nMAssay Description:Inhibition of imatinib-resistant PDGFR D842V mutant (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 642nMAssay Description:Inhibition of imatinib-resistant PDGFR D842V mutant (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of imatinib-resistant BCR-ABL T315I mutant (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50008057(CHEBI:64153 | BMS-722782 | TANESPIMYCIN)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of imatinib-resistant BCR-ABL T315I mutant (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50008057(CHEBI:64153 | BMS-722782 | TANESPIMYCIN)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of imatinib-resistant BCR-ABL T315I mutant (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of imatinib-resistant BCR-ABL T315I mutant (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50008057(CHEBI:64153 | BMS-722782 | TANESPIMYCIN)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of BCR-ABL (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48 hrs by trypan blue exclusion as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of BCR-ABL (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48 hrs by trypan blue exclusion as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of BCR-ABL (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48 hrs by trypan blue exclusion as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50008057(CHEBI:64153 | BMS-722782 | TANESPIMYCIN)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of BCR-ABL (unknown origin) expressed in mouse BA/F3 cells assessed as decrease in cell viability after 48 hrs by trypan blue exclusion as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed