Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50010099
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535185(CHEMBL4464968)
Affinity DataKd:  27nMAssay Description:Binding affinity to 6His-tagged EphA4 C204A mutant (29 to 104 residues) (unknown origin) expressed in Escherichia coli Origami 2 (DE3) by isothermal ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535182(CHEMBL4449863)
Affinity DataKd:  45nMAssay Description:Binding affinity to 6His-tagged EphA4 C204A mutant (29 to 104 residues) (unknown origin) expressed in Escherichia coli Origami 2 (DE3) by isothermal ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535186(CHEMBL4436732)
Affinity DataKd:  30nMAssay Description:Binding affinity to 6His-tagged EphA4 C204A mutant (29 to 104 residues) (unknown origin) expressed in Escherichia coli Origami 2 (DE3) by isothermal ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535195(CHEMBL4530593)
Affinity DataKd:  19nMAssay Description:Binding affinity to 6His-tagged EphA4 C204A mutant (29 to 104 residues) (unknown origin) expressed in Escherichia coli Origami 2 (DE3) by isothermal ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535195(CHEMBL4530593)
Affinity DataIC50: 12nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535199(CHEMBL4462106)
Affinity DataIC50: 12nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535185(CHEMBL4464968)
Affinity DataIC50: 17nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535185(CHEMBL4464968)
Affinity DataIC50: 20nMAssay Description:Antagonist activity against mouse EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535194(CHEMBL4464855)
Affinity DataIC50: 22nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535198(CHEMBL4440005)
Affinity DataIC50: 25nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535186(CHEMBL4436732)
Affinity DataIC50: 27nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535192(CHEMBL4458170)
Affinity DataIC50: 34nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535196(CHEMBL4447628)
Affinity DataIC50: 38nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535193(CHEMBL4539149)
Affinity DataIC50: 40nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535184(CHEMBL4516686)
Affinity DataIC50: 41nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535182(CHEMBL4449863)
Affinity DataIC50: 50nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535200(CHEMBL4434643)
Affinity DataIC50: 54nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535181(CHEMBL4436577)
Affinity DataIC50: 83nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535197(CHEMBL4474623)
Affinity DataIC50: 230nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535185(CHEMBL4464968)
Affinity DataIC50: 240nMAssay Description:Inhibition of 0.5 ug/ml ephrinA5-induced human EphA4 tyrosine phosphorylation expressed in HEK293AD cells preincubated for 20 mins followed by ephrin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535190(CHEMBL4520376)
Affinity DataIC50: 260nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535183(CHEMBL4569881)
Affinity DataIC50: 290nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535195(CHEMBL4530593)
Affinity DataIC50: 310nMAssay Description:Inhibition of 0.4 ug/ml ephrinA5-induced human EphA4 tyrosine phosphorylation expressed in HEK293AD cells preincubated for 20 mins followed by ephrin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535189(CHEMBL4442705)
Affinity DataIC50: 450nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535191(CHEMBL4522324)
Affinity DataIC50: 480nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535188(CHEMBL4591478)
Affinity DataIC50: 920nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535187(CHEMBL4476251)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50535180(CHEMBL4468291)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human EphA4 receptor assessed as inhibition of binding of alkaline phosphatase-fused ephrin-A5 to immobilized EphA4 Fc by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed