Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50011211
TargetTyrosine-protein kinase Yes(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103784(Phosphoric acid mono-(4-{2-acetylamino-2-[(S)-1-(3...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103784(Phosphoric acid mono-(4-{2-acetylamino-2-[(S)-1-(3...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103781((4-{2-Acetylamino-2-[1-(3-carbamoyl-4-cyclohexylme...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103782((4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103780([4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103786((4-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: 3.54E+4nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103781((4-{2-Acetylamino-2-[1-(3-carbamoyl-4-cyclohexylme...)
Affinity DataIC50: 9.45E+4nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103782((4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103780([4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)
Affinity DataIC50: 1.56E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103786((4-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: 3.03E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103787((4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)
Affinity DataIC50: 3.70E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103785({4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmetho...)
Affinity DataIC50: 3.78E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103784(Phosphoric acid mono-(4-{2-acetylamino-2-[(S)-1-(3...)
Affinity DataIC50: 4.41E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103785({4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmetho...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103781((4-{2-Acetylamino-2-[1-(3-carbamoyl-4-cyclohexylme...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103778([5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103788((5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103782((4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103783({4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmetho...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103788((5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103783({4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmetho...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103788((5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103787((4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103778([5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103786((4-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103785({4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmetho...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103783({4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmetho...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103779(Trifluoro-methanesulfonic acid 4-{2-[1-(3-carbamoy...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103779(Trifluoro-methanesulfonic acid 4-{2-[1-(3-carbamoy...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103780([4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103779(Trifluoro-methanesulfonic acid 4-{2-[1-(3-carbamoy...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103778([5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed