Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50012412
TargetDNA-binding protein Ikaros/Protein cereblon(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50557457(CHEMBL4742712)
Affinity DataEC50: >1.00E+4nMAssay Description:Protac activity at CRBN/IKZF1 (unknown origin) assessed as IKZF1 degradationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 2C19(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50557457(CHEMBL4742712)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50557457(CHEMBL4742712)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed