Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50012598
LigandPNGBDBM246383(US9446044, 69)
Affinity DataKd:  7.30nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as dissociation constant at 3 uM by ITC assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 0.590nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 0.590nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
LigandPNGBDBM50434352(CHEMBL2386748 | US9446044, 78)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)
Affinity DataIC50: 0.980nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM246384(US9446044, 71)
Affinity DataIC50: 0.990nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50434352(CHEMBL2386748 | US9446044, 78)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM246384(US9446044, 71)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of DYRK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlycogen synthase kinase-3 alpha(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of GSK3A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of GSK3A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50: 11nMAssay Description:Inhibition of DYRK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 11nMAssay Description:Inhibition of CLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 21nMAssay Description:Inhibition of DYRK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
LigandPNGBDBM100152(cid_5359389 | SMR001233259 | HARMINE | 7-methoxy-1...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50: 23nMAssay Description:Inhibition of CLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 32nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 33nMAssay Description:Inhibition of CLK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataIC50: 37nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM100152(cid_5359389 | SMR001233259 | HARMINE | 7-methoxy-1...)
Affinity DataIC50: 57nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50: 59nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein kinase CLK2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50: 89nMAssay Description:Inhibition of CLK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50: 93nMAssay Description:Inhibition of DYRK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 143nMAssay Description:Inhibition of GSK3B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50: 221nMAssay Description:Inhibition of GSK3B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of CLK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 4(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of DYRK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CLK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed