Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50017132
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 14.6nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 14.6nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 17.6nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
TargetAcetyl-CoA acetyltransferase, mitochondrial(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human ACAT1 in HepG2 cells assessed as inhibition of triglyceride synthesis incubated for 1 hrs followed by 13C-addition of 13C-oleic a...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
TargetAcetyl-CoA acetyltransferase, mitochondrial(Human)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human ACAT1 in HepG2 cells assessed as inhibition of triglyceride synthesis incubated for 1 hrs followed by 13C-addition of 13C-oleic a...More data for this Ligand-Target Pair
