Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50017483
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182718(4-(4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)-5-methy...)
Affinity DataIC50: 148nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM20882(CHEMBL251974 | 4-[4-(4-benzylpiperazin-1-yl)-1H-py...)
Affinity DataIC50: 600nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182707(4-(4-(4-(4-(methylsulfonyl)benzyl)piperazin-1-yl)-...)
Affinity DataIC50: 600nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182712(4-(4-(4-(4-(methylsulfonyl)benzyl)piperazin-1-yl)-...)
Affinity DataIC50: 740nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182712(4-(4-(4-(4-(methylsulfonyl)benzyl)piperazin-1-yl)-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182715(4-chloro-6-(4-(piperazin-1-yl)-1H-pyrazol-3-yl)ben...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182700(4-phenethyl-6-(4-(piperazin-1-yl)-1H-pyrazol-3-yl)...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM20882(CHEMBL251974 | 4-[4-(4-benzylpiperazin-1-yl)-1H-py...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182707(4-(4-(4-(4-(methylsulfonyl)benzyl)piperazin-1-yl)-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182702(4-chloro-6-(5-methyl-4-(piperazin-1-yl)-1H-pyrazol...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182705(4-chloro-6-(4-(4-ethylpiperazin-1-yl)-1H-pyrazol-3...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182710(4-chloro-6-(4-(4-phenethylpiperazin-1-yl)-1H-pyraz...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182709(4-(4-(4-(4-(methylsulfonyl)benzyl)piperazin-1-yl)-...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182703(4-bromo-6-(4-(4-(ethylamino)piperidin-1-yl)-1H-pyr...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182714(5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZ...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182718(4-(4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)-5-methy...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182715(4-chloro-6-(4-(piperazin-1-yl)-1H-pyrazol-3-yl)ben...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182716(5-(4-Piperazin-1-yl-1H-pyrazol-3-yl)-biphenyl-2,4-...)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182717(4-chloro-6-(4-(4-methylpiperazin-1-yl)-1H-pyrazol-...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182714(5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZ...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182700(4-phenethyl-6-(4-(piperazin-1-yl)-1H-pyrazol-3-yl)...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182716(5-(4-Piperazin-1-yl-1H-pyrazol-3-yl)-biphenyl-2,4-...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182711(4-bromo-6-(4-(piperazin-1-yl)-1H-pyrazol-3-yl)benz...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182705(4-chloro-6-(4-(4-ethylpiperazin-1-yl)-1H-pyrazol-3...)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182713(4-(4-(4-(4-(methylsulfonyl)benzylamino)piperidin-1...)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182710(4-chloro-6-(4-(4-phenethylpiperazin-1-yl)-1H-pyraz...)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182719(4-bromo-6-(4-(4-hydroxypiperidin-1-yl)-1H-pyrazol-...)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182699(4-chloro-6-(4-morpholino-1H-pyrazol-3-yl)benzene-1...)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182706(4-chloro-6-(5-(hydroxymethyl)-4-(piperazin-1-yl)-1...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182703(4-bromo-6-(4-(4-(ethylamino)piperidin-1-yl)-1H-pyr...)
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182702(4-chloro-6-(5-methyl-4-(piperazin-1-yl)-1H-pyrazol...)
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182709(4-(4-(4-(4-(methylsulfonyl)benzyl)piperazin-1-yl)-...)
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182701(2-(4-(3-(5-chloro-2,4-dihydroxyphenyl)-1H-pyrazol-...)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of HSP90 by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182713(4-(4-(4-(4-(methylsulfonyl)benzylamino)piperidin-1...)
Affinity DataIC50: 4.03E+4nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182699(4-chloro-6-(4-morpholino-1H-pyrazol-3-yl)benzene-1...)
Affinity DataIC50: 6.87E+4nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182719(4-bromo-6-(4-(4-hydroxypiperidin-1-yl)-1H-pyrazol-...)
Affinity DataIC50: 9.69E+4nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182701(2-(4-(3-(5-chloro-2,4-dihydroxyphenyl)-1H-pyrazol-...)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Vernalis

Curated by ChEMBL
LigandPNGBDBM50182706(4-chloro-6-(5-(hydroxymethyl)-4-(piperazin-1-yl)-1...)
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of HSP90 ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed