Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50017679
TargetSteryl-sulfatase(Human)
Gdask University of Technology

Curated by ChEMBL
LigandPNGBDBM50134329(Sulfamic acid (8R,9S,13S,14S)-13-methyl-17-oxo-7,8...)
Affinity DataIC50: 0.0650nMAssay Description:Inhibition of STS in human MCF7 cells assessed as reduction in [3H]estradiol and [3H]estrone formation using [3H]estrone sulfate as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSteryl-sulfatase(Human)
Gdask University of Technology

Curated by ChEMBL
LigandPNGBDBM50604012(CHEMBL5199004)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of STS in human MCF7 cells using [3H]E1S as substrate incubated for 20 hrs by radioisotope cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSteryl-sulfatase(Human)
Gdask University of Technology

Curated by ChEMBL
LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of STS in human MCF7 cells using [3H]E1S as substrate incubated for 20 hrs by radioisotope cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSteryl-sulfatase(Human)
Gdask University of Technology

Curated by ChEMBL
LigandPNGBDBM50604009(CHEMBL5170413)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of STS in human MCF7 cells using [3H]E1S as substrate incubated for 20 hrs by radioisotope cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSteryl-sulfatase(Human)
Gdask University of Technology

Curated by ChEMBL
LigandPNGBDBM50604011(CHEMBL5205557)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of STS in human MCF7 cells using [3H]E1S as substrate incubated for 20 hrs by radioisotope cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSteryl-sulfatase(Human)
Gdask University of Technology

Curated by ChEMBL
LigandPNGBDBM50604008(CHEMBL5179747)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of STS in human MCF7 cells using [3H]E1S as substrate incubated for 20 hrs by radioisotope cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSteryl-sulfatase(Human)
Gdask University of Technology

Curated by ChEMBL
LigandPNGBDBM50604010(CHEMBL5169672)
Affinity DataIC50: 3nMAssay Description:Inhibition of STS in human MCF7 cells using [3H]E1S as substrate incubated for 20 hrs by radioisotope cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSteryl-sulfatase(Human)
Gdask University of Technology

Curated by ChEMBL
LigandPNGBDBM50604012(CHEMBL5199004)
Affinity DataIC50: 37nMAssay Description:Inhibition of human placental STS using [3H]E1S as substrate incubated for 3 hrs by radioisotope enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSteryl-sulfatase(Human)
Gdask University of Technology

Curated by ChEMBL
LigandPNGBDBM50051829(4-methyl-2-oxo-2H-chromen-7-yl sulfamate | Sulfami...)
Affinity DataIC50: 380nMAssay Description:Inhibition of STS in human MCF7 cells assessed as reduction in [3H]estradiol and [3H]estrone formation using [3H]estrone sulfate as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed