Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50019553
Target5-hydroxytryptamine receptor 2A(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM139370(ACP-103 | Pimavanserin | Pimavanserin hydrochlorid...)
Affinity DataIC50: 5nMAssay Description:Inverse agonist activity at human prefrontal cortex 5-HT2A receptor assessed as increase in [35S]GTPgammaS binding by liquid scintillation spectromet...More data for this Ligand-Target Pair
In DepthDetails
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM50620434(CHEMBL5414080)
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at human prefrontal cortex 5-HT2A receptor assessed as increase in [35S]GTPgammaS binding by liquid scintillation spectromet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM631402(US20230348421, Compound 31)
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at human prefrontal cortex 5-HT2A receptor assessed as increase in [35S]GTPgammaS binding by liquid scintillation spectromet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM50620435(CHEMBL5403965)
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at human prefrontal cortex 5-HT2A receptor assessed as increase in [35S]GTPgammaS binding by liquid scintillation spectromet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM139370(ACP-103 | Pimavanserin | Pimavanserin hydrochlorid...)
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at human 5-HT2A receptor expressed in cell membrane assessed as increase in [35S]GTPgammaS binding by liquid scintillation s...More data for this Ligand-Target Pair
In DepthDetails
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM50620434(CHEMBL5414080)
Affinity DataIC50: 79nMAssay Description:Inverse agonist activity at human 5-HT2A receptor expressed in cell membrane assessed as increase in [35S]GTPgammaS binding by liquid scintillation s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM631402(US20230348421, Compound 31)
Affinity DataIC50: 79nMAssay Description:Inverse agonist activity at human 5-HT2A receptor expressed in cell membrane assessed as increase in [35S]GTPgammaS binding by liquid scintillation s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM50620435(CHEMBL5403965)
Affinity DataIC50: 79nMAssay Description:Inverse agonist activity at human 5-HT2A receptor expressed in cell membrane assessed as increase in [35S]GTPgammaS binding by liquid scintillation s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM631402(US20230348421, Compound 31)
Affinity DataKi:  0.00300nMAssay Description:Displacement of [3H]ketanserin human recombinant 5-HT2A receptor by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
The University of Jordan

Curated by ChEMBL
LigandPNGBDBM631402(US20230348421, Compound 31)
Affinity DataKi:  0.0600nMAssay Description:Displacement of [3H]ketanserin from human brain cortex 5-HT2A receptor by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
PubMed