Compile Data Set for Download or QSAR
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Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50020075
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210107(7-chloro-3-(4-chlorophenylsulfonyl)quinazoline-2,4...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210098(6-(4,5-dichloro-2-methoxybenzyl)-4-(4-chlorophenyl...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210116(6-(5-fluoro-2-methoxybenzyl)-4-(4-chlorophenylsulf...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210094(3-((1-(4-chlorophenylsulfonyl)-3,7-dioxo-1,4-diaze...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210120((S)-6-(5-chloro-2-methoxybenzyl)-4-(4-chlorophenyl...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM100740(CHEMBL391608 | US8507714, 29)
Affinity DataIC50:  34nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210099(CHEMBL246964 | rac-2q)
Affinity DataIC50:  39nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210096(2-(4-chloro-2-((1-(4-chlorophenylsulfonyl)-3,7-dio...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM87059(CHEMBL247767 | Chymostatin)
Affinity DataIC50:  43nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210113(6-(5-chloro-2-ethoxybenzyl)-4-(4-chlorophenylsulfo...)
Affinity DataIC50:  83nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210097(6-(2-chlorobenzyl)-4-(4-chlorophenylsulfonyl)-1,4-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210115(6-(2-methoxybenzyl)-4-(4-chlorophenylsulfonyl)-1,4...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210121(6-(2-fluorobenzyl)-4-(4-chlorophenylsulfonyl)-1,4-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210109(6-(2-ethoxybenzyl)-4-(4-chlorophenylsulfonyl)-1,4-...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210110(6-(5-chloro-2-propoxybenzyl)-4-(4-chlorophenylsulf...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210114(6-(2-butoxy-5-chlorobenzyl)-4-(4-chlorophenylsulfo...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210118(6-(3-chlorobenzyl)-4-(4-chlorophenylsulfonyl)-1,4-...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210117(6-benzyl-4-(4-chlorophenylsulfonyl)-1,4-diazepane-...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210106(6-(4-chlorobenzyl)-4-(4-chlorophenylsulfonyl)-1,4-...)
Affinity DataIC50:  460nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210108(6-(5-hydroxy-2-methoxybenzyl)-4-(4-chlorophenylsul...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210105((E)-6-benzylidene-4-(4-chlorophenylsulfonyl)-1,4-d...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM100740(CHEMBL391608 | US8507714, 29)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human neutrophil cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210101(6-(3-chloro-5-fluoro-2-methoxybenzyl)-4-(4-chlorop...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210103(6-(2,5-dimethoxybenzyl)-4-(4-chlorophenylsulfonyl)...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210095(4-(4-chlorophenylsulfonyl)-6-(pyridin-4-ylmethyl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM100740(CHEMBL391608 | US8507714, 29)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210111(4-(4-chlorophenylsulfonyl)-6-(cyclohexylmethyl)-1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210102(4-(4-chlorophenylsulfonyl)-6-(naphthalen-2-ylmethy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210104((R)-6-(5-chloro-2-methoxybenzyl)-4-(4-chlorophenyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50210119(4-(4-chlorophenylsulfonyl)-6-(pyridin-3-ylmethyl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed