Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50021429
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CCR2 expressed in THP1 cells assessed as MCP1-induced calcium fluxMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 16.7nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 660nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Mouse)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [125I]-rat MCP1 from rat CCR2 receptor in monocytesMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Mouse)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [125I]-mouse MCP1 from CCR2 in mouse WEHI265.1 cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Mouse)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [125I]-mouse MCP1 from CCR2 in mouse peripheral blood monocytesMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human CCR2More data for this Ligand-Target Pair
