Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50025054
Target5-hydroxytryptamine receptor 2A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50241702([N-methyl-3H]LSD | CHEMBL463207)
Affinity DataKd:  21.2nMAssay Description:Binding affinity to human 5HT2A receptor expressed in HEK293 cells by saturation binding methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2C(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50241702([N-methyl-3H]LSD | CHEMBL463207)
Affinity DataKd:  52.8nMAssay Description:Binding affinity to human 5HT2C receptor expressed in HEK293 cells by saturation binding methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKd:  15.8nMAssay Description:Binding affinity to human 5HT4 receptor expressed in HEK293 cells by saturation binding methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50031942(CHEMBL1065 | Sansert | (6aR,9R)-4-Methyl-4,6,6a,7,...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [N-methyl-3H]LSD from human 5HT2C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50031942(CHEMBL1065 | Sansert | (6aR,9R)-4-Methyl-4,6,6a,7,...)
Affinity DataKi:  10nMAssay Description:Displacement of [N-methyl-3H]LSD from human 5HT2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  20nMAssay Description:Displacement of [N-methyl-3H]LSD from human 5HT2C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataKi:  31nMAssay Description:Displacement of [N-methyl-3H]GR-113808 from human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50234920(Barettin | cyclo[(6-bromo-8-entryptophan)arginine]...)
Affinity DataKi:  340nMAssay Description:Displacement of [N-methyl-3H]LSD from human 5HT2C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  500nMAssay Description:Displacement of [N-methyl-3H]GR-113808 from human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  690nMAssay Description:Displacement of [N-methyl-3H]LSD from human 5HT2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50234920(Barettin | cyclo[(6-bromo-8-entryptophan)arginine]...)
Affinity DataKi:  1.91E+3nMAssay Description:Displacement of [N-methyl-3H]GR-113808 from human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50234920(Barettin | cyclo[(6-bromo-8-entryptophan)arginine]...)
Affinity DataKi:  1.93E+3nMAssay Description:Displacement of [N-methyl-3H]LSD from human 5HT2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50241836(cyclo[(6-bromotryptophan)arginine] | CHEMBL511609)
Affinity DataKi:  4.63E+3nMAssay Description:Displacement of [N-methyl-3H]LSD from human 5HT2C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50241836(cyclo[(6-bromotryptophan)arginine] | CHEMBL511609)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [N-methyl-3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50241836(cyclo[(6-bromotryptophan)arginine] | CHEMBL511609)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [1,2-3H]5-carboxamidotryptamine from human 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50241836(cyclo[(6-bromotryptophan)arginine] | CHEMBL511609)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [1,2-3H]5-carboxamidotryptamine from human 5HT7A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50234920(Barettin | cyclo[(6-bromo-8-entryptophan)arginine]...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [1,2-3H]5-carboxamidotryptamine from human 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50234920(Barettin | cyclo[(6-bromo-8-entryptophan)arginine]...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [1,2-3H]5-carboxamidotryptamine from human 5HT1D receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50234920(Barettin | cyclo[(6-bromo-8-entryptophan)arginine]...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [9-methyl-3H]BRL-43694 from human 5HT3A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50241836(cyclo[(6-bromotryptophan)arginine] | CHEMBL511609)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [1,2-3H]5-carboxamidotryptamine from human 5HT5A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50241836(cyclo[(6-bromotryptophan)arginine] | CHEMBL511609)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [N-methyl-3H]GR-113808 from human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50241836(cyclo[(6-bromotryptophan)arginine] | CHEMBL511609)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [9-methyl-3H]BRL-43694 from human 5HT3A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50241836(cyclo[(6-bromotryptophan)arginine] | CHEMBL511609)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [N-methyl-3H]LSD from human 5HT2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50241836(cyclo[(6-bromotryptophan)arginine] | CHEMBL511609)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [1,2-3H]5-carboxamidotryptamine from human 5HT1D receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50234920(Barettin | cyclo[(6-bromo-8-entryptophan)arginine]...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [1,2-3H]5-carboxamidotryptamine from human 5HT7A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50234920(Barettin | cyclo[(6-bromo-8-entryptophan)arginine]...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [N-methyl-3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50234920(Barettin | cyclo[(6-bromo-8-entryptophan)arginine]...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [1,2-3H]5-carboxamidotryptamine from human 5HT5A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed