Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50028743
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of human PXRMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CARM1 assessed as blockade of histone H3 methylationMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3 [N508S](Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PRMT3 by methylation assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PRMT1 by methylation assayMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 expressed in human hepatocytesMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C9 expressed in human hepatocytesMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C19 expressed in human hepatocytesMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6 expressed in human hepatocytesMore data for this Ligand-Target Pair
