Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50030194
TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]sulpiride from dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50001023((2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]pirenzepine from muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandPNGBDBM50064176(METHOCTRAMINE | N,N''-Bis-[6-(2-methoxy-benzylamin...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]AF-DX384 from muscarinic M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50292408(5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11E,14Z-...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]LTD4 from LTD4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]DAGO from mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50292411(Actahist | CHEMBL855 | Actifed | Myfed | Triphed |...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM31046(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]RX781094 from alpha2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50013889(5,12-Dihete | CHEMBL65061 | LTB4 | 5,12-Hete | (S-...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]LTB4 from LTB4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThromboxane A2 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50292409((Z)-7-((1R,4S,5S,6R)-6-((S,E)-3-hydroxyoct-1-enyl)...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]SQ29548 from thromboxane A2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50008369(cid_8974 | 2-(6-Amino-2-chloro-purin-9-yl)-5-hydro...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandPNGBDBM50010859(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]citalopram from serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50005548((+/-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquin...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]WIN-from cocaine site of dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50292410(Butaclamol | 3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataKi:  580nMAssay Description:Displacement of [3H]DMI from norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)