Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50030618
TargetEphrin type-B receptor 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(Cpd66 | 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of EphB1 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(Cpd66 | 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of EphB2 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(Cpd66 | 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of EphB4 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(Cpd66 | 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of EphA2 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-A receptor 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(Cpd66 | 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of EphA1 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-A receptor 5(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(Cpd66 | 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of EphA5 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(Cpd66 | 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of EphA4 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-A receptor 8(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(Cpd66 | 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of EphA8 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(Cpd66 | 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(Cpd66 | 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of EphB3 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(Cpd66 | 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of EphA3 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299219(8-(2-Methoxyphenyl)-1-methyl-7-o-methylphenyl-1H-i...)
Affinity DataIC50: 47nMAssay Description:Inhibition of EphB4 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299219(8-(2-Methoxyphenyl)-1-methyl-7-o-methylphenyl-1H-i...)
Affinity DataIC50: 180nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299220(8-(2-Methoxyphenyl)-1-methyl-7-m-hydroxyphenyl-1H-...)
Affinity DataIC50: 213nMAssay Description:Inhibition of EphB4 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299221(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-4'-hydro...)
Affinity DataIC50: 236nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299220(8-(2-Methoxyphenyl)-1-methyl-7-m-hydroxyphenyl-1H-...)
Affinity DataIC50: 368nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299222(8-(Butyl)-1-methyl-7-p-hydroxyphenyl-1H-imidazo[2,...)
Affinity DataIC50: 558nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299223(8-(Butyl)-1-methyl-7-m-hydroxyphenyl-1H-imidazo[2,...)
Affinity DataIC50: 691nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-A receptor 7(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(Cpd66 | 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of EphA7 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299224(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-3'-hydro...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299225(8-(Butyl)-1-methyl-7-o-hydroxyphenyl-1H-imidazo[2,...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299226(8-(2-methoxyphenyl)-1-methyl-7-phenyl-1H-imidazo[1...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299226(8-(2-methoxyphenyl)-1-methyl-7-phenyl-1H-imidazo[1...)
Affinity DataIC50: 4.35E+3nMAssay Description:Inhibition of EphB4 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299227(8-(2-Methoxyphenyl)-1-methyl-7-(2',5'-dihydroxyphe...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299228(7-p-Fluorophenyl-8-(2-methoxyphenyl)-1H-imidazo[2,...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50234863(8-(4-hydroxybutyl)-1-methyl-7-phenyl-1H-imidazo[1,...)
Affinity DataIC50: 5.68E+3nMAssay Description:Inhibition of EphB4 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50234863(8-(4-hydroxybutyl)-1-methyl-7-phenyl-1H-imidazo[1,...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299232(1-Benzyl-8-(2-methoxyphenyl)-7-phenyl-1H-imidazo[2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299233(1-Benzyl-7-p-fluorophenyl-8-(2-methoxyphenyl)-1H-i...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299234(8-(Butyl)-1-methyl-7-o-methoxyphenyl-1H-imidazo[2,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299235(8-(Butyl)-1-methyl-7-p-methoxyphenyl-1H-imidazo[2,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299236(8-(2-Methoxyphenyl)-1-methyl-7-m-methylphenyl-1H-i...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299229(8-(2-Methoxyphenyl)-1-methyl-7-p-nitrophenyl-1H-im...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299230(8-(2-Methoxyphenyl)-1-methyl-7-p-cyanophenyl-1H-im...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299231(8-(2-Methoxyphenyl)-1-methyl-7-p-carboxyphenyl-1H-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299237(7-(Benzo[d][1,3]dioxol-5-yl)-8-(2-methoxyphenyl)-1...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed