Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50031081
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306617((S)-1-fluoro-3-((S)-3-(3-(1,1,2,2-tetrafluoroethox...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306608((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 41nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306607((S)-3-((S)-8-(3,5-difluorophenyl)-3-(3-(1,1,2,2-te...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306619((S)-1-((S)-3-(3-(1,1,2,2-tetrafluoroethoxy)phenyl)...)
Affinity DataIC50: 88nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306611((S)-1,1,1-trifluoro-3-((S)-3-(3-(trifluoromethoxy)...)
Affinity DataIC50: 94nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306612((S)-3-((S)-3,8-bis(3-(trifluoromethoxy)phenyl)-2H-...)
Affinity DataIC50: 107nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306602(3-methyl-1-(3-(3-(1,1,2,2-tetrafluoroethoxy)phenyl...)
Affinity DataIC50: 129nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306612((S)-3-((S)-3,8-bis(3-(trifluoromethoxy)phenyl)-2H-...)
Affinity DataIC50: 133nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306618((R)-1-fluoro-3-((S)-3-(3-(1,1,2,2-tetrafluoroethox...)
Affinity DataIC50: 147nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306604(4-propyl-3-(3-(1,1,2,2-tetrafluoroethoxy)phenyl)-8...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306610((S)-3-((S)-8-(3,5-difluorophenyl)-3-(3-(trifluorom...)
Affinity DataIC50: 193nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306613(3-(3-(3-chlorophenyl)-8-(3-(trifluoromethoxy)pheny...)
Affinity DataIC50: 214nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306616(3-(3-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-8-(3-(...)
Affinity DataIC50: 271nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306606(1,1,1-trifluoro-3-(8-(3-fluorophenyl)-3-(3-(1,1,2,...)
Affinity DataIC50: 322nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306615(1,1,1-trifluoro-3-(8-(3-(trifluoromethoxy)phenyl)-...)
Affinity DataIC50: 360nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306614(3-(3-(3-ethoxyphenyl)-8-(3-(trifluoromethoxy)pheny...)
Affinity DataIC50: 490nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306603(2-methyl-1-(3-(3-(1,1,2,2-tetrafluoroethoxy)phenyl...)
Affinity DataIC50: 560nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306609((S)-3-((S)-8-(3,5-bis(trifluoromethyl)phenyl)-3-(3...)
Affinity DataIC50: 580nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of cholesteryl ester transfer protein in human plasma by [3H]CE HDL assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 tissue isoform in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 muscle isoform in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed