Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50032101
TargetProthrombin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324477(CHEMBL1215085 | CHEMBL1229261 | Benzylsulfonyl-D-c...)
Affinity DataKi:  0.102nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324478(CHEMBL1215086 | CHEMBL1229262 | Benzylsulfonyl-D-c...)
Affinity DataKi:  0.108nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324476(Benzylsulfonyl-D-arginyl-proline-(2-aminomethyl-5-...)
Affinity DataKi:  1nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324475(CHEMBL1229259 | CHEMBL1215083 | Benzylsulfonyl-D-a...)
Affinity DataKi:  1.94nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSuppressor of tumorigenicity 14 protein(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324475(CHEMBL1229259 | CHEMBL1215083 | Benzylsulfonyl-D-a...)
Affinity DataKi:  55nMAssay Description:Inhibition of human recombinant matriptase catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324475(CHEMBL1229259 | CHEMBL1215083 | Benzylsulfonyl-D-a...)
Affinity DataKi:  170nMAssay Description:Inhibition of human purified matriptase 2 catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324475(CHEMBL1229259 | CHEMBL1215083 | Benzylsulfonyl-D-a...)
Affinity DataKi:  190nMAssay Description:Inhibition of human recombinant matriptase 2 expressed in HEK293 cells in conditioned medium after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324476(Benzylsulfonyl-D-arginyl-proline-(2-aminomethyl-5-...)
Affinity DataKi:  220nMAssay Description:Inhibition of human recombinant matriptase catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324477(CHEMBL1215085 | CHEMBL1229261 | Benzylsulfonyl-D-c...)
Affinity DataKi:  290nMAssay Description:Inhibition of human recombinant matriptase 2 expressed in HEK293 cells in conditioned medium after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324477(CHEMBL1215085 | CHEMBL1229261 | Benzylsulfonyl-D-c...)
Affinity DataKi:  460nMAssay Description:Inhibition of human purified matriptase 2 catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324477(CHEMBL1215085 | CHEMBL1229261 | Benzylsulfonyl-D-c...)
Affinity DataKi:  770nMAssay Description:Inhibition of human recombinant matriptase catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50286441(Ac-LLR-CHO | Ac-Leu-Leu-Arg-H | (S)-2-((S)-2-Acety...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of human recombinant matriptase catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324478(CHEMBL1215086 | CHEMBL1229262 | Benzylsulfonyl-D-c...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of human recombinant matriptase catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50286441(Ac-LLR-CHO | Ac-Leu-Leu-Arg-H | (S)-2-((S)-2-Acety...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human recombinant matriptase 2 expressed in HEK293 cells in conditioned medium after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50286441(Ac-LLR-CHO | Ac-Leu-Leu-Arg-H | (S)-2-((S)-2-Acety...)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of human purified matriptase 2 catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324476(Benzylsulfonyl-D-arginyl-proline-(2-aminomethyl-5-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant matriptase 2 expressed in HEK293 cells in conditioned medium after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324476(Benzylsulfonyl-D-arginyl-proline-(2-aminomethyl-5-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human purified matriptase 2 catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324478(CHEMBL1215086 | CHEMBL1229262 | Benzylsulfonyl-D-c...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant matriptase 2 expressed in HEK293 cells in conditioned medium after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50324478(CHEMBL1215086 | CHEMBL1229262 | Benzylsulfonyl-D-c...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human purified matriptase 2 catalytic domain expressed in HEK293 cells after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed