Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50032255
TargetSodium/glucose cotransporter 2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50326284(1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50326280(1-(beta-D-Glucopyranosyl)-4-chloro-3-(5-chloro-2-t...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM20877(CHEMBL183937 | JMC511145 Compound 2 | 3-(1-benzofu...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50326283(1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50326279(1-(beta-D-Glucopyranosyl)-3-(5-ethyl-2-thienylmeth...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50326282(1-(beta-D-Glucopyranosyl)-4-chloro-3-(2-ethyl-5-py...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50326281(1-(beta-D-Glucopyranosyl)-4-chloro-3-(1-phenyl-1H-...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM20877(CHEMBL183937 | JMC511145 Compound 2 | 3-(1-benzofu...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50326284(1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...)
Affinity DataIC50: 910nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50326278(1-(beta-D-Glucopyranosyl)-3-(5-ethyl-2-furylmethyl...)
Affinity DataIC50: 920nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM20877(CHEMBL183937 | JMC511145 Compound 2 | 3-(1-benzofu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GLUT1-mediated [3H]2-deoxy-glucose uptake in rat L6 cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50326284(1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GLUT1-mediated [3H]2-deoxy-glucose uptake in rat L6 cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed