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Report error Found 98 Enz. Inhib. hit(s) with all data for entry = 50032386
TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328377(CHEMBL1258375 | ethyl 6-(3-tert-butyl-1,2,4-oxadia...)
Affinity DataIC50:  19nMAssay Description:Inhibition of DGAT1 in human Caco2 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328378(CHEMBL1258829 | ethyl 6-(3-cyclopentyl-1,2,4-oxadi...)
Affinity DataIC50: <30nMAssay Description:Inhibition of DGAT1 in human Caco2 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328379(CHEMBL1258944 | ethyl 6-(3-cyclohexyl-1,2,4-oxadia...)
Affinity DataIC50:  31nMAssay Description:Inhibition of DGAT1 in human Caco2 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328378(CHEMBL1258829 | ethyl 6-(3-cyclopentyl-1,2,4-oxadi...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328377(CHEMBL1258375 | ethyl 6-(3-tert-butyl-1,2,4-oxadia...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328380(CHEMBL1258148 | ethyl 6-(3-isopropyl-1,2,4-oxadiaz...)
Affinity DataIC50:  51nMAssay Description:Inhibition of DGAT1 in human Caco2 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328342(CHEMBL1258943 | diethyl 7-(4-methoxyphenyl)-2-morp...)
Affinity DataIC50:  52nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328379(CHEMBL1258944 | ethyl 6-(3-cyclohexyl-1,2,4-oxadia...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328380(CHEMBL1258148 | ethyl 6-(3-isopropyl-1,2,4-oxadiaz...)
Affinity DataIC50:  57nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328343(CHEMBL1256010 | diethyl 7-(4-(benzyloxy)phenyl)-2-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328381(CHEMBL1258147 | ethyl 2-morpholino-4-phenyl-7-prop...)
Affinity DataIC50:  65nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328344(CHEMBL1258708 | diethyl 7-(4-chlorophenyl)-2-morph...)
Affinity DataIC50:  68nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328382(CHEMBL1258263 | ethyl 6-(3-butyl-1,2,4-oxadiazol-5...)
Affinity DataIC50:  69nMAssay Description:Inhibition of DGAT1 in human Caco2 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328382(CHEMBL1258263 | ethyl 6-(3-butyl-1,2,4-oxadiazol-5...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328345(CHEMBL1257799 | diethyl 7-allyl-2-morpholino-4-phe...)
Affinity DataIC50:  75nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328383(CHEMBL1258709 | ethyl 6-(3-benzyl-1,2,4-oxadiazol-...)
Affinity DataIC50:  77nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328346(CHEMBL1258374 | diethyl 2-morpholino-4,7-diphenylp...)
Affinity DataIC50:  81nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328377(CHEMBL1258375 | ethyl 6-(3-tert-butyl-1,2,4-oxadia...)
Affinity DataIC50:  83nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328384(CHEMBL1257209 | ethyl 2-morpholino-4-phenyl-7-prop...)
Affinity DataIC50:  100nMAssay Description:Inhibition of DGAT1 in human Caco2 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328384(CHEMBL1257209 | ethyl 2-morpholino-4-phenyl-7-prop...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328343(CHEMBL1256010 | diethyl 7-(4-(benzyloxy)phenyl)-2-...)
Affinity DataIC50: <100nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328386(CHEMBL1258488 | ethyl 2-morpholino-6-(3-pentyl-1,2...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328385(CHEMBL1258030 | ethyl 6-(3-ethyl-1,2,4-oxadiazol-5...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328347(CHEMBL1257800 | diethyl 2-morpholino-4-phenyl-7-(3...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328366(CHEMBL1257328 | diethyl 4-phenyl-7-propyl-2-(pyrro...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328341(CHEMBL1257556 | diethyl 2-morpholino-4-phenyl-7-pr...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328383(CHEMBL1258709 | ethyl 6-(3-benzyl-1,2,4-oxadiazol-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328387(CHEMBL1257329 | ethyl 6-(3-(dimethylamino)-1,2,4-o...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328348(CHEMBL1257917 | diethyl 7-butyl-2-morpholino-4-phe...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328389(CHEMBL1257330 | ethyl 7-(2-hydroxyethyl)-2-morphol...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328388(CHEMBL1258601 | ethyl 2-morpholino-4-phenyl-6-(3-p...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328387(CHEMBL1257329 | ethyl 6-(3-(dimethylamino)-1,2,4-o...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328388(CHEMBL1258601 | ethyl 2-morpholino-4-phenyl-6-(3-p...)
Affinity DataIC50:  200nMAssay Description:Inhibition of DGAT1 in human Caco2 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328349(CHEMBL1257918 | diethyl 2-morpholino-7-pentyl-4-ph...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328344(CHEMBL1258708 | diethyl 7-(4-chlorophenyl)-2-morph...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328378(CHEMBL1258829 | ethyl 6-(3-cyclopentyl-1,2,4-oxadi...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328351(CHEMBL1258146 | diethyl 7-(methoxymethyl)-2-morpho...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328350(CHEMBL1257678 | diethyl 7-ethyl-2-morpholino-4-phe...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328352(CHEMBL1256009 | diethyl 7-(biphenyl-4-yl)-2-morpho...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328391(CHEMBL1257443 | diethyl 2-morpholino-4-phenyl-7-pr...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328381(CHEMBL1258147 | ethyl 2-morpholino-4-phenyl-7-prop...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328389(CHEMBL1257330 | ethyl 7-(2-hydroxyethyl)-2-morphol...)
Affinity DataIC50:  260nMAssay Description:Inhibition of DGAT1 in human Caco2 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328370(CHEMBL1257559 | diethyl 4-(3-fluorophenyl)-2-morph...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328353(CHEMBL1258261 | diethyl 7-(3-methoxypropyl)-2-morp...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328371(CHEMBL1257679 | diethyl 4-(4-fluorophenyl)-2-morph...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328354(CHEMBL1258600 | diethyl 7-(3-chlorophenyl)-2-morph...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328349(CHEMBL1257918 | diethyl 2-morpholino-7-pentyl-4-ph...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328352(CHEMBL1256009 | diethyl 7-(biphenyl-4-yl)-2-morpho...)
Affinity DataIC50: <300nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328348(CHEMBL1257917 | diethyl 7-butyl-2-morpholino-4-phe...)
Affinity DataIC50: <300nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328354(CHEMBL1258600 | diethyl 7-(3-chlorophenyl)-2-morph...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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