Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50032856
TargetCasein kinase II subunit alpha(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant CK2alpha by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant CK2alpha at enzyme-substrate complex by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335639(7-((1H-tetrazol-5-yl)methyl)indolo[1,2-a]quinazoli...)
Affinity DataIC50: 12nMAssay Description:Inhibition of PARP1 at 1 uM by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant DAPK3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant TBK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant CLK3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHomeodomain-interacting protein kinase 3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant HIPK3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant PIM1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant FLT3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant CDK1/Cyclin B by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335641(4-Oxo-4,5-dihydrothieno[3,2-c]quinoline-7-carboxam...)
Affinity DataIC50: 60nMAssay Description:Inhibition of PARP1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335642(7-(Hydroxymethyl)thieno[3,2-c]quinolin-4(5H)-one |...)
Affinity DataIC50: 400nMAssay Description:Inhibition of PARP1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50335640(4-Oxo-4,5-dihydrothieno[3,2-c]quinoline-7-carboxyl...)
Affinity DataIC50: 700nMAssay Description:Inhibition of PARP1 by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed