Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50033998
TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human DGAT-1-mediated triglyceride synthesis in the HT-29 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50355144(CHEMBL1834554)
Affinity DataIC50:  10nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50355142(CHEMBL1835919)
Affinity DataIC50:  16nMAssay Description:Inhibition of human DGAT-1-mediated triglyceride synthesis in the HT-29 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50355145(CHEMBL1833980)
Affinity DataIC50:  18nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50355142(CHEMBL1835919)
Affinity DataIC50:  19nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50355144(CHEMBL1834554)
Affinity DataIC50:  34nMAssay Description:Inhibition of human DGAT-1-mediated triglyceride synthesis in the HT-29 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50355145(CHEMBL1833980)
Affinity DataIC50:  77nMAssay Description:Inhibition of human DGAT-1-mediated triglyceride synthesis in the HT-29 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50355146(CHEMBL1834555)
Affinity DataIC50:  98nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50355147(CHEMBL1834556)
Affinity DataIC50:  175nMAssay Description:Inhibition of human DGAT-1-mediated triglyceride synthesis in the HT-29 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50355148(CHEMBL1834557)
Affinity DataIC50:  225nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50355149(CHEMBL1834558)
Affinity DataIC50:  245nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50355147(CHEMBL1834556)
Affinity DataIC50:  249nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50355143(CHEMBL1835920)
Affinity DataIC50:  265nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50355149(CHEMBL1834558)
Affinity DataIC50:  735nMAssay Description:Inhibition of human DGAT-1-mediated triglyceride synthesis in the HT-29 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed