Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50038185
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50206310(ELACRIDAR HYDROCHLORIDE | N-4-[2-(1,2,3,4-Tetrahyd...)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50372889(CHEMBL261391)
Affinity DataEC50:  2.50E+3nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234488(N-[(3,4-dimethoxy)benzyl]-2-[2-(3-methoxyphenyl)et...)
Affinity DataEC50:  500nMAssay Description:Inhibition of human BCRP pump mediated [3H]mitoxantrone transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234479(1,2-dimethoxy-4-((2-(3-methoxyphenethyl)phenoxy)me...)
Affinity DataEC50:  1.50E+5nMAssay Description:Inhibition of human BCRP pump mediated [3H]mitoxantrone transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50197199(1-(benzyloxy)-2-phenethylbenzene | 1-(benzyloxy)-2...)
Affinity DataEC50: >1.00E+6nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50372890(CHEMBL272892)
Affinity DataEC50:  850nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50372891(CHEMBL270688)
Affinity DataEC50:  1.80E+4nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50197200(2-((2-(3-methoxyphenethyl)phenoxy)methyl)pyridine ...)
Affinity DataEC50:  2.76E+4nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50197197(2-{[2-(2-phenylethyl)phenoxy]methyl}pyridine | 2-(...)
Affinity DataEC50:  1.00E+5nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234488(N-[(3,4-dimethoxy)benzyl]-2-[2-(3-methoxyphenyl)et...)
Affinity DataEC50:  180nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50372892(CHEMBL259030)
Affinity DataEC50:  900nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234476(N-[(2,3-dimethoxy)benzyl]-2-[2-(3-methoxyphenyl)et...)
Affinity DataEC50:  85nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50372888(CHEMBL406597)
Affinity DataEC50:  480nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50372893(CHEMBL270557)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234479(1,2-dimethoxy-4-((2-(3-methoxyphenethyl)phenoxy)me...)
Affinity DataEC50:  650nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50411102(CHEMBL384538)
Affinity DataEC50:  9.56E+4nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50338982((R)-5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3...)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50197196(3-({2-[2-(3-methoxyphenyl)ethyl]phenoxy}methyl)pyr...)
Affinity DataEC50: >1.00E+6nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234481(1,2-dimethoxy-3-((2-(3-methoxyphenethyl)phenoxy)me...)
Affinity DataEC50:  250nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50372883(CHEMBL258611)
Affinity DataEC50:  800nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50372884(CHEMBL406618)
Affinity DataEC50:  5.20E+3nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50372885(CHEMBL405348)
Affinity DataEC50:  3.10E+3nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50197198(1-[(3-methoxybenzyl)oxy]-2-[2-(3-methoxyphenyl)eth...)
Affinity DataEC50:  1.72E+4nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50372886(CHEMBL260731)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50372887(CHEMBL271353)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50197201(1-(2-(benzyloxy)phenethyl)-3-methoxybenzene | 1-(b...)
Affinity DataEC50:  9.28E+4nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50372882(CHEMBL270559)
Affinity DataEC50:  750nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50372883(CHEMBL258611)
Affinity DataEC50:  7.50E+4nMAssay Description:Inhibition of human BCRP pump mediated [3H]mitoxantrone transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234476(N-[(2,3-dimethoxy)benzyl]-2-[2-(3-methoxyphenyl)et...)
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibition of human BCRP pump mediated [3H]mitoxantrone transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50372888(CHEMBL406597)
Affinity DataEC50:  7.00E+3nMAssay Description:Inhibition of human BCRP pump mediated [3H]mitoxantrone transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50372882(CHEMBL270559)
Affinity DataEC50:  5.80E+4nMAssay Description:Inhibition of human BCRP pump mediated [3H]mitoxantrone transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234481(1,2-dimethoxy-3-((2-(3-methoxyphenethyl)phenoxy)me...)
Affinity DataEC50:  1.20E+5nMAssay Description:Inhibition of human BCRP pump mediated [3H]mitoxantrone transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50197195(3-{[2-(2-phenylethyl)phenoxy]methyl}pyridine | 3-(...)
Affinity DataEC50:  1.25E+5nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataEC50:  8.00E+4nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed