Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50039244
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322696(CHEMBL1173087 | rac-6-(3,4-dichlorophenyl)-5-metho...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human CYP2D6 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322696(CHEMBL1173087 | rac-6-(3,4-dichlorophenyl)-5-metho...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human CYP2C19 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322696(CHEMBL1173087 | rac-6-(3,4-dichlorophenyl)-5-metho...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human CYP2C9 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322696(CHEMBL1173087 | rac-6-(3,4-dichlorophenyl)-5-metho...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human CYP1A2 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322696(CHEMBL1173087 | rac-6-(3,4-dichlorophenyl)-5-metho...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human CYP3A4 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human CYP2D6 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human CYP2D6 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human CYP2D6 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322697(1-(methoxymethyl)-6-(naphthalen-2-yl)-3-azabicyclo...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human CYP1A2 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322697(1-(methoxymethyl)-6-(naphthalen-2-yl)-3-azabicyclo...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human CYP2C9 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322697(1-(methoxymethyl)-6-(naphthalen-2-yl)-3-azabicyclo...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human CYP2C19 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322697(1-(methoxymethyl)-6-(naphthalen-2-yl)-3-azabicyclo...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human CYP2D6 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322697(1-(methoxymethyl)-6-(naphthalen-2-yl)-3-azabicyclo...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human CYP3A4 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C19 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP1A2 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C9 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C19 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP3A4 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP1A2 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C9 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C19 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP3A4 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP1A2 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C9 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP3A4 after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataKi:  1.58nMAssay Description:Displacement of [3H]-citalopram from SERT in mouse cortex after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataKi:  1.58nMAssay Description:Displacement of [3H]nisoxetine from NET in mouse brainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetTransporter(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataKi:  2.51nMAssay Description:Displacement of [3H]nisoxetine from NET in rat hippocampus after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]WIN-35428 from DAT in mouse brainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed