Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50043474
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441646(CHEMBL2437421)
Affinity DataKd:  2nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441640(CHEMBL2437427)
Affinity DataKd:  6.30nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441639(CHEMBL2437428)
Affinity DataKd:  13nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441638(CHEMBL2437429)
Affinity DataKd:  5nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441637(CHEMBL2437430)
Affinity DataKd:  2nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441654(CHEMBL2437431)
Affinity DataKd:  16nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441653(CHEMBL2437432)
Affinity DataKd:  10nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441641(CHEMBL2437426)
Affinity DataKd:  2nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441642(CHEMBL2437425)
Affinity DataKd:  2nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441643(CHEMBL2437424)
Affinity DataKd:  2.5nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441644(CHEMBL2437423)
Affinity DataKd:  1.30nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441647(CHEMBL2437420)
Affinity DataKd:  10nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441651(CHEMBL2437417)
Affinity DataKd:  7.90nMAssay Description:Antagonist activity at histamine H3 receptor in electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441643(CHEMBL2437424)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441653(CHEMBL2437432)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441654(CHEMBL2437431)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441637(CHEMBL2437430)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441638(CHEMBL2437429)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441639(CHEMBL2437428)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441640(CHEMBL2437427)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441641(CHEMBL2437426)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441642(CHEMBL2437425)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441652(CHEMBL2437433)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441644(CHEMBL2437423)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441645(CHEMBL2437422)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441646(CHEMBL2437421)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441647(CHEMBL2437420)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441651(CHEMBL2437417)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441649(CHEMBL2437416)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441652(CHEMBL2437433)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441649(CHEMBL2437416)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441646(CHEMBL2437421)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441637(CHEMBL2437430)
Affinity DataKi:  0.950nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441647(CHEMBL2437420)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441642(CHEMBL2437425)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441641(CHEMBL2437426)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441645(CHEMBL2437422)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441654(CHEMBL2437431)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441638(CHEMBL2437429)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441644(CHEMBL2437423)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441653(CHEMBL2437432)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441651(CHEMBL2437417)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441640(CHEMBL2437427)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441655(CHEMBL2437415)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441643(CHEMBL2437424)
Affinity DataKi:  7.60nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441656(CHEMBL2437414)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441639(CHEMBL2437428)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441650(CHEMBL2437418)
Affinity DataKi:  77nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H3 receptor(Guinea pig)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50441648(CHEMBL2437419)
Affinity DataKi:  420nMAssay Description:Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed