Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50044390
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015538(CHEMBL3265330)
Affinity DataIC50: 20nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015546(CHEMBL3265334)
Affinity DataIC50: 60nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015541(CHEMBL3265331)
Affinity DataIC50: 80nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015543(CHEMBL3265332)
Affinity DataIC50: 90nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015538(CHEMBL3265330)
Affinity DataIC50: 110nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015546(CHEMBL3265334)
Affinity DataIC50: 110nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015547(CHEMBL3265335)
Affinity DataIC50: 130nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015545(CHEMBL3265333)
Affinity DataIC50: 140nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015541(CHEMBL3265331)
Affinity DataIC50: 150nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015545(CHEMBL3265333)
Affinity DataIC50: 300nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015543(CHEMBL3265332)
Affinity DataIC50: 360nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015560(CHEMBL3265338)
Affinity DataIC50: 420nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015547(CHEMBL3265335)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015547(CHEMBL3265335)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015550(CHEMBL3265337)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015550(CHEMBL3265337)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015538(CHEMBL3265330)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015548(CHEMBL3265336)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50015560(CHEMBL3265338)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed