Compile Data Set for Download or QSAR
Report error Found 144 Enz. Inhib. hit(s) with all data for entry = 50045337
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057761(CHEMBL3322994)
Affinity DataIC50: 0.00380nMAssay Description:Antagonist activity against human D3R expressed in CHO cells assessed as inhibition of dopamine-induced [35S]GTPgammaS binding by dopamine potency sh...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 0.0600nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 0.160nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057761(CHEMBL3322994)
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057763(CHEMBL3323016 | US9598387, Compound 115 | US996974...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057767(CHEMBL3323017 | US9598387, Compound 116 | US996974...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057763(CHEMBL3323016 | US9598387, Compound 115 | US996974...)
Affinity DataIC50: 0.330nMAssay Description:Antagonist activity against human D3R expressed in CHO cells assessed as inhibition of dopamine-induced [35S]GTPgammaS binding by dopamine potency sh...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057768(CHEMBL3323015 | US9598387, Compound 114 | US996974...)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057762(CHEMBL3323011 | US9598387, Compound 113 | US996974...)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057772(CHEMBL3322993)
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057761(CHEMBL3322994)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity against human D2LR expressed in CHO cells assessed as inhibition of dopamine-induced [35S]GTPgammaS binding by dopamine potency s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057762(CHEMBL3323011 | US9598387, Compound 113 | US996974...)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity against human D3R expressed in CHO cells assessed as inhibition of dopamine-induced [35S]GTPgammaS binding by dopamine potency sh...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057773(CHEMBL3322995)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057772(CHEMBL3322993)
Affinity DataIC50: 3nMAssay Description:Antagonist activity against human D3R expressed in CHO cells assessed as inhibition of quinpirole-induced mitogenesis after 24 hrs by [3H]thymidine u...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057771(CHEMBL3323012)
Affinity DataIC50: 5.60nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057772(CHEMBL3322993)
Affinity DataIC50: 6.60nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057759(CHEMBL3323117)
Affinity DataIC50: 6.80nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057753(CHEMBL3323112 | US9598387, Compound 120 | US996974...)
Affinity DataIC50: 7.20nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057761(CHEMBL3322994)
Affinity DataIC50: 7.20nMAssay Description:Antagonist activity against human D3R expressed in CHO cells assessed as inhibition of quinpirole-induced mitogenesis after 24 hrs by [3H]thymidine u...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057770(CHEMBL3323013)
Affinity DataIC50: 8.5nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057749(CHEMBL3323019)
Affinity DataIC50: 14nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057759(CHEMBL3323117)
Affinity DataIC50: 19nMAssay Description:Antagonist activity against human D3R expressed in CHO cells assessed as inhibition of dopamine-induced [35S]GTPgammaS binding by dopamine potency sh...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057767(CHEMBL3323017 | US9598387, Compound 116 | US996974...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057763(CHEMBL3323016 | US9598387, Compound 115 | US996974...)
Affinity DataIC50: 25nMAssay Description:Antagonist activity against human D2LR expressed in CHO cells assessed as inhibition of dopamine-induced [35S]GTPgammaS binding by dopamine potency s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057772(CHEMBL3322993)
Affinity DataIC50: 26nMAssay Description:Antagonist activity against human D2R expressed in CHO cells assessed as inhibition of quinpirole-induced mitogenesis after 24 hrs by [3H]thymidine u...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057757(CHEMBL3323114 | US9598387, Compound 121 | US996974...)
Affinity DataIC50: 29nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057768(CHEMBL3323015 | US9598387, Compound 114 | US996974...)
Affinity DataIC50: 37nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057763(CHEMBL3323016 | US9598387, Compound 115 | US996974...)
Affinity DataIC50: 49nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057768(CHEMBL3323015 | US9598387, Compound 114 | US996974...)
Affinity DataIC50: 51nMAssay Description:Antagonist activity against human D3R expressed in CHO cells assessed as inhibition of quinpirole-induced mitogenesis after 24 hrs by [3H]thymidine u...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057774(CHEMBL3322998 | US9598387, Compound 117 | US996974...)
Affinity DataIC50: 52nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057761(CHEMBL3322994)
Affinity DataIC50: 55nMAssay Description:Antagonist activity against human D2R expressed in CHO cells assessed as inhibition of quinpirole-induced mitogenesis after 24 hrs by [3H]thymidine u...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057773(CHEMBL3322995)
Affinity DataIC50: 60nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057761(CHEMBL3322994)
Affinity DataIC50: 91nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057762(CHEMBL3323011 | US9598387, Compound 113 | US996974...)
Affinity DataIC50: 111nMAssay Description:Antagonist activity against human D2LR expressed in CHO cells assessed as inhibition of dopamine-induced [35S]GTPgammaS binding by dopamine potency s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057774(CHEMBL3322998 | US9598387, Compound 117 | US996974...)
Affinity DataIC50: 120nMAssay Description:Antagonist activity against human D3R expressed in CHO cells assessed as inhibition of quinpirole-induced mitogenesis after 24 hrs by [3H]thymidine u...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057762(CHEMBL3323011 | US9598387, Compound 113 | US996974...)
Affinity DataIC50: 157nMAssay Description:Antagonist activity against human D3R expressed in CHO cells assessed as inhibition of quinpirole-induced mitogenesis after 24 hrs by [3H]thymidine u...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057774(CHEMBL3322998 | US9598387, Compound 117 | US996974...)
Affinity DataIC50: 161nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057768(CHEMBL3323015 | US9598387, Compound 114 | US996974...)
Affinity DataIC50: 205nMAssay Description:Antagonist activity against human D2R expressed in CHO cells assessed as inhibition of quinpirole-induced mitogenesis after 24 hrs by [3H]thymidine u...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057770(CHEMBL3323013)
Affinity DataIC50: 208nMAssay Description:Antagonist activity against human D3R expressed in CHO cells assessed as inhibition of quinpirole-induced mitogenesis after 24 hrs by [3H]thymidine u...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057753(CHEMBL3323112 | US9598387, Compound 120 | US996974...)
Affinity DataIC50: 217nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057763(CHEMBL3323016 | US9598387, Compound 115 | US996974...)
Affinity DataIC50: 245nMAssay Description:Antagonist activity against human D3R expressed in CHO cells assessed as inhibition of quinpirole-induced mitogenesis after 24 hrs by [3H]thymidine u...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057775(CHEMBL3323003 | US9598387, Compound 127 | US996974...)
Affinity DataIC50: 248nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057762(CHEMBL3323011 | US9598387, Compound 113 | US996974...)
Affinity DataIC50: 261nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057757(CHEMBL3323114 | US9598387, Compound 121 | US996974...)
Affinity DataIC50: 281nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057770(CHEMBL3323013)
Affinity DataIC50: 301nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057749(CHEMBL3323019)
Affinity DataIC50: 311nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057775(CHEMBL3323003 | US9598387, Compound 127 | US996974...)
Affinity DataIC50: 409nMAssay Description:Antagonist activity against D3R in human U2OS cells assessed as inhibition of (+)-PD128907-induced beta-arrestin translocation by beta-galactosidase ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057771(CHEMBL3323012)
Affinity DataIC50: 418nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057763(CHEMBL3323016 | US9598387, Compound 115 | US996974...)
Affinity DataIC50: 420nMAssay Description:Antagonist activity against human D2R expressed in CHO cells assessed as inhibition of quinpirole-induced mitogenesis after 24 hrs by [3H]thymidine u...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50057770(CHEMBL3323013)
Affinity DataIC50: 490nMAssay Description:Antagonist activity against human D2R expressed in CHO cells assessed as inhibition of quinpirole-induced mitogenesis after 24 hrs by [3H]thymidine u...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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