Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50046875
LigandPNGBDBM50134771(CHEMBL3754515)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50134771(CHEMBL3754515)
Affinity DataIC50: 8nMAssay Description:Inhibition of MINK (unknown origin) in presence of ATP (Km)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138160(CHEMBL3753424)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50134771(CHEMBL3754515)
Affinity DataIC50: 15nMAssay Description:Inhibition of TNIK (unknown origin) in presence of ATP (Km)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50134772(CHEMBL3754123)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138128(CHEMBL3754730)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138153(CHEMBL3754283)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50138158(CHEMBL3752854)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50134774(CHEMBL3754588)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138162(CHEMBL3752433)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138155(CHEMBL3754304)
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138151(CHEMBL3753371)
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50134773(CHEMBL3752536)
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138135(CHEMBL3754762)
Affinity DataIC50: 96nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50134771(CHEMBL3754515)
Affinity DataIC50: 160nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138134(CHEMBL3754611)
Affinity DataIC50: 248nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138127(CHEMBL3753891)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138160(CHEMBL3753424)
Affinity DataIC50: 360nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50134772(CHEMBL3754123)
Affinity DataIC50: 470nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138128(CHEMBL3754730)
Affinity DataIC50: 590nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138158(CHEMBL3752854)
Affinity DataIC50: 600nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138137(CHEMBL3754522)
Affinity DataIC50: 861nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138143(CHEMBL3753160)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138159(CHEMBL3752670)
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50134771(CHEMBL3754515)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human ERG transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138153(CHEMBL3754283)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50138135(CHEMBL3754762)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50134771(CHEMBL3754515)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138155(CHEMBL3754304)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138162(CHEMBL3752433)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50134773(CHEMBL3752536)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50134774(CHEMBL3754588)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138162(CHEMBL3752433)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 1 mM ATP by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50134773(CHEMBL3752536)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138134(CHEMBL3754611)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 1 mM ATP by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50134772(CHEMBL3754123)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138159(CHEMBL3752670)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138137(CHEMBL3754522)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138134(CHEMBL3754611)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
LigandPNGBDBM50138127(CHEMBL3753891)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed