Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50047927
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 7nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50135226(CHEMBL3747473)
Affinity DataIC50: 60nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197521(CHEMBL3922351)
Affinity DataIC50: 550nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197518(CHEMBL3747171)
Affinity DataIC50: 690nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197520(CHEMBL3921251)
Affinity DataIC50: 790nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50135226(CHEMBL3747473)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197518(CHEMBL3747171)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197520(CHEMBL3921251)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human COX2 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197521(CHEMBL3922351)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197521(CHEMBL3922351)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human COX2 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197520(CHEMBL3921251)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197518(CHEMBL3747171)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human COX2 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50135226(CHEMBL3747473)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human COX2 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant human COX2 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin E synthase(Mouse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50197516(CHEMBL3961576)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of ovine COX1 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed